Premenstrual tension
MONDO:0004169A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.
Also known as: PMS, premenstrual syndrome
54 clinical trials for this condition and its sub-types, 46 tagged with Premenstrual tension itself.
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Sub-types of Premenstrual tension
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Premenstrual dysphoric disorder 14 trials
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Psilocybin microdoses put to the test for severe PMS mood symptoms
Symptom relief Not yet recruitingResearchers are testing whether a psilocybin-based drug called MLS101 is safe and tolerable for premenopausal women with premenstrual dysphoric disorder (PMDD), a condition that causes intense mood and physical symptoms before menstruation. The trial enrolls 32 women aged 18 to 5…
Phase 1 • Sponsor: MycoMedica Life Sciences PBC • Aim: Symptom relief
Last updated Sep 16, 2026 00:00 UTC
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Can a gentle massage technique calm PMS symptoms and the nervous system?
Symptom relief Not yet recruitingResearchers are testing whether manual lymphatic drainage, a gentle massage that supports lymph flow, can ease premenstrual symptoms and change autonomic nervous system activity in women with PMS. Sixty women aged 18 to 40 will be assigned to one of three groups: drainage perform…
Sponsor: Izmir Democracy University • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Could a foot massage tame premenstrual syndrome?
Symptom relief Not yet recruitingResearchers are testing whether regular foot reflexology can reduce premenstrual syndrome (PMS) symptoms and improve quality of life in female university students aged 18 to 25. Half the participants will receive 30-minute foot reflexology sessions four times a month for three mo…
Sponsor: Dokuz Eylul University • Aim: Symptom relief
Last updated Sep 05, 2026 00:00 UTC
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Coloring your way to calm: mandala art may soothe PMS anxiety and sleep woes
Symptom relief Not yet recruitingThis trial tests whether coloring mandalas—intricate circular patterns—can help reduce anxiety and improve sleep quality in female students who experience premenstrual syndrome (PMS). Participants will be asked to color mandalas, and researchers will measure changes in their anxi…
Sponsor: Kırklareli University • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
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Can a jog or a massage sharpen your memory during PMS?
Symptom relief Not yet recruitingThis study compares two non-drug approaches—aerobic exercise and a specific neck massage technique—to see if they can improve memory in women with premenstrual syndrome (PMS). Researchers will enroll 40 women aged 18 to 30 who have PMS and memory complaints. Participants will be …
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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New study tests sleep workshop as Drug-Free aid for PMDD
Symptom relief Not yet recruitingThis study tests a brief sleep-focused workshop for people with PMDD who have trouble sleeping. The workshop teaches about sleep and simple strategies to improve it. Researchers want to see if it's practical and helpful, using sleep diaries and activity watches. 72 participants w…
Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Can an ancient herb ease PMS? new study seeks answers
Symptom relief Not yet recruitingThis study tests whether shatavari (Asparagus racemosus) root extract can help relieve premenstrual syndrome (PMS) symptoms like mood swings, irritability, and fatigue. Sixty women with mild to moderate PMS will take either the herb or a placebo daily for 12 weeks. Researchers wi…
Sponsor: SF Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Can learning about comfort reduce period cramps? new study investigates
Symptom relief Not yet recruitingThis study tests whether a comfort theory-based education program can help university students with primary dysmenorrhea (painful periods) feel better. The program involves three face-to-face sessions over three months, each lasting 40 minutes. Researchers will compare pain level…
Sponsor: Ordu University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could a tiny dose of LSD ease PMS? new study investigates
Symptom relief Not yet recruitingThis study tests whether very low doses of LSD (10 micrograms) taken daily or every other day during the premenstrual phase can reduce symptoms of severe PMS or PMDD. 150 women will be randomly assigned to LSD or placebo for three menstrual cycles. The goal is to see if LSD can s…
Sponsor: Friederike Holze • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Can a traditional chinese herb ease PMS symptoms?
Symptom relief Not yet recruitingThis study will look at whether Honghua Xiaoyao tablets, a traditional Chinese medicine, can help relieve symptoms of premenstrual syndrome (PMS) in 266 women aged 18 to 40. The researchers will track symptom changes using a daily diary and compare women who take the tablets to t…
Sponsor: Lianxin Wang • Aim: Symptom relief
Last updated Jun 26, 2026 17:05 UTC
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Tape your way to better PMS days? new study tests kinesio taping for mood and pain
Symptom relief Not yet recruitingThis study tests whether kinesio taping, a stretchy tape applied to the skin, can reduce premenstrual syndrome (PMS) symptoms and boost happiness and quality of life. Researchers will compare real taping to a sham (fake) taping in 42 women over 18 who have regular cycles and scor…
Sponsor: Yağmur SÜRMELİ • Aim: Symptom relief
Last updated Jun 26, 2026 13:41 UTC
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Could a hyperactive immune system fuel PMDD? a new study investigates
Knowledge-focused Not yet recruitingThis study explores whether inflammation in the body is linked to the mood and psychological symptoms of Premenstrual Dysphoric Disorder (PMDD). Researchers will compare women with PMDD to healthy controls, tracking daily emotions and behaviors over two menstrual cycles and takin…
Sponsor: King's College London • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC
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New study links menstrual cycle to emotional struggles in autistic women
Knowledge-focused Not yet recruitingThis study looks at how emotional regulation varies across the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any diagnosed condition. The goal is to better underst…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC