Personality disorder
MONDO:0002028A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual's culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work.
Also known as: personality disorder, personality disorder (disease)
172 clinical trials for this condition and its sub-types, 24 tagged with Personality disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Personality disorder
-
Borderline personality disorder 74 trials
-
Schizotypal personality disorder 20 trials
-
Antisocial personality disorder 12 trials
-
Narcissistic personality disorder 2 trials
-
Avoidant personality disorder 1 trial
-
Dependent personality disorder 0 trials
-
Histrionic personality disorder 0 trials
-
Paranoid personality disorder 0 trials
-
Schizoid personality disorder 0 trials
-
Zapping the brain to curb cravings: new hope for dual diagnosis patients?
Disease control CompletedThis study tested a noninvasive brain stimulation technique (transcranial random noise stimulation) to see if it could reduce cravings in 225 adults with substance use disorder plus another psychiatric condition like ADHD, bipolar disorder, or schizophrenia. The approach targeted…
Sponsor: Spanish Foundation for Neurometrics Development • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
-
Drugs and therapy together: a new hope for anxiety, depression, and more?
Disease control CompletedThis early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disord…
Phase 1 • Sponsor: Rakitzi, Stavroula • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
-
New staged treatment shows promise for preventing psychosis in At-Risk youth
Disease control CompletedThis study tested a step-by-step treatment approach for 342 young people aged 12-25 who are at ultra high risk of developing psychosis. The goal was to see if a sequence of therapies and medications could improve daily functioning and reduce the chance of psychosis. The approach …
Phase 3 • Sponsor: Orygen • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
-
Can talk therapy cut crime risk in people with personality disorders?
Disease control CompletedThis study looked at whether schema therapy, a type of talk therapy, can help people with personality disorders who are in outpatient forensic care. Five participants received therapy for up to two years. Researchers measured changes in their thinking patterns, risk of re-offendi…
Sponsor: Vrije Universiteit Brussel • Aim: Disease control
Last updated Jun 26, 2026 19:11 UTC
-
Caregiver support program shows promise for families facing eating disorders
Symptom relief CompletedThis study tested a program called Family Connections for caregivers of people with both an eating disorder and a personality disorder. The goal was to see if the program could reduce stress and conflict at home. 124 Spanish caregivers took part, and researchers measured things l…
Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
-
New combo therapy shows promise for eating disorders
Symptom relief CompletedThis study tested a new combination of two talk therapies for adults with eating disorders who are not underweight. Twenty participants were randomly assigned to either standard cognitive behavioral therapy (CBT-E) or a mix of CBT and metacognitive interpersonal therapy (CBT-F+MI…
Sponsor: Centro Trattamento Integrato: Disturbi Alimentari e Obesita • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
-
Can a 12-Hour course make you a better listener in a crisis?
Knowledge-focused CompletedThis study looked at whether a 12-hour online training course in psychological first aid (based on the RAPID model) could improve people's communication and listening skills. Ten participants completed the training and were tested before and after. The goal was to see if such tra…
Sponsor: Abant Izzet Baysal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
-
Brain scans reveal how your communication style changes your brain
Knowledge-focused CompletedThis study looked at how different ways of communicating (like talking in person vs. texting) change brain activity. Researchers used fMRI scans on 30 healthy young adults while they watched videos of different communication styles. The goal was to see if each style uses a differ…
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
-
Hospital study reveals who gets help for addiction in the ER
Knowledge-focused CompletedThis study looked back at the records of 652 patients who were seen in the emergency department of a French hospital and then referred to a special addiction liaison team. The goal was to understand the social and medical backgrounds of these patients. The findings could help hos…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
-
Brain scans and thinking tests aim to unlock secrets of Self-Harm
Knowledge-focused CompletedThis study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
-
Can therapy plus job help get people back to work faster?
Knowledge-focused CompletedThis study tested whether combining mental health treatment with job coaching helps people on sick leave due to anxiety, depression, stress, personality disorders, or functional disorders return to work. 900 participants in Denmark received either the combined service or usual ca…
Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
-
Your temperament may shape your menopause experience
Knowledge-focused CompletedThis study looked at whether a woman's natural temperament (like being more anxious or upbeat) is linked to how severe her menopause symptoms are. Researchers surveyed 105 women going through menopause using two standard questionnaires. The goal was simply to understand connectio…
Sponsor: Bagcilar Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC