Osteoarthritis, hand

This study is testing a device called KeriFuse® that is implanted into the finger joint to fuse the bones together. It is for people with arthritis in the last joint of the finger or thumb. The goal is to see if it reduces pain and successfully fuses the joint within three months…

This trial compares two surgical procedures for people with painful thumb base osteoarthritis that hasn't improved with conservative care. One procedure removes the entire trapezium bone, while the other removes only a small portion to create a narrow gap. The study will track pa…

This trial tests whether injecting platelet-rich plasma (PRP) into the thumb joint can reduce pain and improve function in people with thumb base osteoarthritis. Participants are randomly assigned to receive either PRP or a saline placebo injection, and neither they nor the resea…

This study tests whether methotrexate, a drug used for other types of arthritis, can reduce pain and improve hand function in people with a severe form of hand osteoarthritis. About 163 adults with moderate to severe finger pain will receive either methotrexate or a placebo for 6…

This study is testing a new thumb joint replacement called the Touch® prosthesis in 216 adults with severe thumb osteoarthritis. The implant is designed to reduce pain and improve thumb mobility. Researchers will check how well it works and how safe it is over time, starting at 3…

This trial tests whether suzetrigine (Journavx), a newly approved non-opioid pain medication, can effectively control pain after thumb basal joint replacement surgery. One hundred adults aged 40 to 80 will receive suzetrigine plus acetaminophen for five days after surgery, and th…

This early study tests an injection called Allocetra for osteoarthritis at the base of the thumb. The trial includes 46 adults aged 40 and older whose pain hasn't improved with standard treatments. Researchers are checking if the injection is safe and whether it can reduce pain a…

This study tests whether using a lower-pressure tourniquet during orthopedic surgeries can reduce pain and the need for opioid painkillers afterward. Standard tourniquets use high pressure, which can cause muscle weakness and pain. The experimental device sets pressure based on t…

This study looks at whether a 6-day course of oral steroids after orthopedic surgery can help reduce pain, nausea, and improve movement. About 500 adults having common surgeries like joint replacement or fracture repair will be randomly assigned to receive either standard care or…

This early-stage trial is testing whether injecting donated fat tissue into the small joints of the hand can reduce pain and improve movement in people with hand osteoarthritis. About 34 adults with joint pain and X-ray evidence of arthritis will receive the injection under local…

This study tests whether turmeric (curcumin) can reduce pain and improve function in people with thumb-joint arthritis. One hundred adults will take turmeric capsules for four weeks and a placebo for another four weeks, then compare results. The goal is to see if this common spic…

This study tests whether injecting botulinum toxin into the thumb joint can reduce pain and improve function in people with thumb osteoarthritis (rhizarthrosis). Sixty adults with moderate to severe pain who have not responded to standard painkillers will receive either botulinum…

This study tests whether adding high-intensity laser therapy to a standard exercise program can better reduce pain and improve function in people with thumb osteoarthritis. 48 participants with stage I-III thumb joint arthritis will receive laser treatment three times a week for …

This study uses artificial intelligence to analyze X-rays and CT scans of the thumb joint affected by osteoarthritis. Researchers aim to develop automated tools to classify disease severity, detect implant loosening, and create 3D models for better surgical planning. The study in…

This study tests whether giving patients with hand problems like carpal tunnel syndrome or trigger finger a decision aid—a booklet with clear information about their condition and treatment options—helps them feel more satisfied and less conflicted about their choices. About 126 …

This study was designed to see if a pre-surgery meeting with an occupational therapist helps people with hand injuries or thumb arthritis recover faster and attend their therapy appointments. It planned to include adults needing surgery for a broken wrist, a cut tendon, or thumb …