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AI could revolutionize thumb arthritis diagnosis and monitoring

NCT ID NCT07148349

Knowledge-focused Sponsor: Schulthess Klinik Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses artificial intelligence to analyze X-rays and CT scans of the thumb joint affected by osteoarthritis. Researchers aim to develop automated tools to classify disease severity, detect implant loosening, and create 3D models for better surgical planning. The study involves 2500 patients from a Swiss clinic and is focused on improving assessment methods, not testing a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to more accurate and automated tools for diagnosing thumb osteoarthritis and monitoring implants, improving surgical planning.
What could go wrong
This is an early-stage, retrospective study using existing data. The AI tools are for research only and not yet ready for clinical use. They may not work as well in real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of patients treated at Schulthess Klinik Zürich with available radiographic imaging of the TMC joint. Data are derived from two cohorts: (1) patients enrolled in the TMC arthroplasty registry (BASEC number: 2019-02096) who received a Touch implant since 2018, and (2) patients with other wrist-related conditions requiring radiographs in which the TMC joint is clearly visible. The combined cohorts provide a balanced representation across the spectrum of TMC joint OA severity, from healthy joints to end-stage disease.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: Patients will be included in the study if they have provided written general consent for the use of their clinical data and meet the requirements of one of the following two groups: TMC OA group: • Patients who received a Touch implant for TMC joint arthroplasty and are documented in our clinical registry Other clinical conditions: • Patients who underwent radiographic imaging for one of the following conditions, with a clearly visible TMC joint, for example: Distal radius fracture, carpal fracture, finger dislocation, or similar. Exclusion Criteria: The exclusion criteria are defined based on the two inclusion groups: TMC OA group: * Patients with posttraumatic OA. * Patients with rheumatoid arthritis. Other clinical conditions: * Eaton Littler score higher than one. * Prior surgery affecting the trapezium or the first metacarpal. * Clinical condition resulting in abnormal TMC joint morphology. Furthermore, patients will also be excluded if they revoke their consent in writing or via verbal withdrawal.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, hand

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thumb osteoarthritis

Contacts and locations

Locations

  • Schulthess Klinik

    Zurich, Canton of Zurich, 8008, Switzerland

More trials for these conditions

Other studies related to the condition(s) this trial covers.