Neuromuscular disease
MONDO:0019056Any disease that impairs the functioning of the muscles, either directly, being pathologies of the voluntary muscle, or indirectly, being pathologies of nerves or neuromuscular junctions
Also known as: nerve and muscle disorder, neuromuscular disease
2353 clinical trials for this condition and its sub-types, 112 tagged with Neuromuscular disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Neuromuscular disease
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Peripheral neuropathy 93 trials · 1,473 incl. sub-types
30 sub-types
- Hereditary peripheral neuropathy 6 trials · 479 incl. sub-types Sub-types →
- Neuralgia 238 trials · 384 incl. sub-types Sub-types →
- Nerve compression syndrome 24 trials · 207 incl. sub-types Sub-types →
- Diabetic neuropathy 182 trials · 193 incl. sub-types Sub-types →
- Chemotherapy-induced neuropathy 171 trials
- Polyneuropathy 32 trials · 133 incl. sub-types Sub-types →
- Mononeuropathy 4 trials · 112 incl. sub-types Sub-types →
- Acquired peripheral neuropathy 0 trials · 95 incl. sub-types Sub-types →
- Nerve plexus disorder 0 trials · 75 incl. sub-types Sub-types →
- Sensory peripheral neuropathy 4 trials · 58 incl. sub-types Sub-types →
- Traumatic neuropathy 55 trials
- Neuritis 18 trials · 29 incl. sub-types Sub-types →
- Peripheral nerve lesion 1 trial · 12 incl. sub-types Sub-types →
- Autonomic neuropathy 7 trials · 10 incl. sub-types Sub-types →
- Chronic idiopathic neuropathy 5 trials
- Axonal neuropathy 1 trial · 4 incl. sub-types Sub-types →
- Neuropathy, small fiber 4 trials
- Infectious neuropathy 2 trials
- Vasculitic neuropathy 2 trials
- Autoimmune neuropathy 1 trial
- Idiopathic small fibers neuropathy 1 trial
- Ischemic neuropathy 1 trial
- Motor peripheral neuropathy 0 trials · 1 incl. sub-types Sub-types →
- Radiation-induced neuropathy 0 trials · 1 incl. sub-types Sub-types →
- Sarcoid neuropathy 1 trial
- Neuropathy in cryoglobulinemia 0 trials
- Neuropathy in endocrine disorder 0 trials
- Paraproteinemia-associated neuropathy 0 trials
- Uremic neuropathy 0 trials
- Vitamin deficiency related neuropathy 0 trials
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Hereditary neuromuscular disease 3 trials · 935 incl. sub-types
22 sub-types
- Hereditary peripheral neuropathy 6 trials · 479 incl. sub-types Sub-types →
- Muscular dystrophy 74 trials · 290 incl. sub-types Sub-types →
- Hereditary motor neuron disease 1 trial · 169 incl. sub-types Sub-types →
- Hereditary spastic paraplegia 27 trials · 33 incl. sub-types Sub-types →
- Benign paroxysmal positional vertigo 18 trials
- Meniere disease 16 trials Sub-types →
- RYR1-related myopathy 5 trials · 6 incl. sub-types Sub-types →
- Congenital myasthenic syndrome 6 trials Sub-types →
- Malignant hyperthermia of anesthesia 5 trials
- SCN4A-related channelopathy 1 trial · 2 incl. sub-types Sub-types →
- Early-onset myopathy with fatal cardiomyopathy 1 trial
- Andersen-Tawil syndrome 0 trials
- CNGB3-related retinopathy 0 trials Sub-types →
- KY-related neuromyopathy 0 trials Sub-types →
- Morimoto-Ryu-Malicdan neuromuscular syndrome 0 trials
- X-linked recessive mitochondrial myopathy 0 trials
- Myofibrillar myopathy 1 0 trials
- Myotonia congenita, autosomal dominant 0 trials
- Myotonia congenita, autosomal recessive 0 trials
- Neuromuscular disorder, congenital, with dysmorphic facies 0 trials
- Periodic paralysis with later-onset distal motor neuropathy 0 trials
- Vertigo, benign recurrent, 1 0 trials
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Motor neuron disorder 70 trials · 510 incl. sub-types
4 sub-types
- Amyotrophic lateral sclerosis 331 trials · 345 incl. sub-types Sub-types →
- Hereditary motor neuron disease 1 trial · 169 incl. sub-types Sub-types →
- Acquired motor neuron disease 0 trials · 39 incl. sub-types Sub-types →
- Madras motor neuron disease 0 trials
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Vestibular disorder 64 trials · 92 incl. sub-types
1 sub-type
- Peripheral vertigo 2 trials · 34 incl. sub-types Sub-types →
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Muscular channelopathy 0 trials · 19 incl. sub-types
12 sub-types
- Thomsen and Becker disease 9 trials Sub-types →
- RYR1-related myopathy 5 trials · 6 incl. sub-types Sub-types →
- Malignant hyperthermia of anesthesia 5 trials
- SCN4A-related channelopathy 1 trial · 2 incl. sub-types Sub-types →
- Andersen-Tawil syndrome 0 trials
- CNGB3-related retinopathy 0 trials Sub-types →
- Isaac syndrome 0 trials
- Morvan syndrome 0 trials
- Neurological muscular channelopathy due to a genetic calcium channel defect 0 trials
- Neurological muscular channelopathy due to a genetic chloride channel defect 0 trials
- Neurological muscular channelopathy due to a genetic potassium channel defect 0 trials
- Neurological muscular channelopathy due to a genetic sodium channel defect 0 trials
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Atrophic muscular disease 7 trials
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Neuromuscular junction disease 1 trial · 7 incl. sub-types
1 sub-type
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Akinetopsia 0 trials
Most studied deeper sub-types
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Can gene therapy help babies with SMA reach milestones? a Real-World review
Disease control Not yet recruitingThis study looks back at medical records of children with spinal muscular atrophy (SMA) type 1 who received a one-time gene therapy called onasemnogene abeparvovec (Zolgensma). Researchers want to see if treated infants can sit independently for 30 seconds or more within a year. …
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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3D-Printed hand braces could be cheaper and just as effective
Symptom relief Not yet recruitingThis study compares 3D-printed hand orthoses (braces) to traditional custom-made ones in 100 adults with chronic hand conditions from nerve, muscle, or bone issues. The goal is to see if the 3D-printed versions work just as well for daily activities, are more satisfying, and cost…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Robot suit aims to get kids with disabilities walking
Symptom relief Not yet recruitingThis study tests a robotic exoskeleton called CLINICAL EXPLORER in 60 children aged 2 to 17 with neurodevelopmental disorders like cerebral palsy. The device supports walking during 8 therapy sessions. Researchers will check if it is safe, easy to use, and helps improve movement …
Sponsor: MarsiBionics • Aim: Symptom relief
Last updated Jun 26, 2026 14:47 UTC
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Can Sauna-Like heat help chronic pain? new study investigates
Knowledge-focused Not yet recruitingThis study looks at how whole-body heat therapy (hyperthermia) changes body temperature, pain sensitivity, and pain during movement in 60 people—half with chronic widespread pain (like fibromyalgia) and half healthy. Participants will receive six heat sessions over three weeks. T…
Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Wearable sensors could transform CMT1A monitoring
Knowledge-focused Not yet recruitingThis study will use wearable activity trackers to measure how much people with Charcot-Marie-Tooth disease type 1A (CMT1A) move at home. Researchers want to see if sensor data matches standard clinical tests. The goal is to improve patient follow-up and support future trials of n…
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Which works better for CMT foot problems: surgery or therapy alone?
Knowledge-focused Not yet recruitingThis study looks at two ways to help people with Charcot-Marie-Tooth disease (CMT) walk better. One group gets foot surgery followed by rehabilitation, the other gets only physical therapy. Researchers will track walking speed and endurance for up to two years to see which approa…
Sponsor: Peking University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New registry aims to improve care for muscular dystrophy patients
Knowledge-focused Not yet recruitingThis study is creating a registry for people with Duchenne and Becker muscular dystrophy, as well as symptomatic female carriers. The goal is to collect health data and quality-of-life information to monitor how new therapies work in real-world settings. Up to 1,500 participants …
Sponsor: Dr. Andreas Ziegler • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New telemedicine approach aims to catch decline in fragile patients early
Knowledge-focused Not yet recruitingThis observational study will follow 100 medically fragile adults with conditions like stroke, multiple sclerosis, Parkinson's disease, or certain fractures. The goal is to see if remote check-ins via video calls can reliably spot declines in mobility and thinking, compared to in…
Sponsor: Azienda Sanitaria Locale CN2 Alba-Bra • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Hidden heart risks in kids with brain conditions?
Knowledge-focused Not yet recruitingThis study looks at 70 children aged 1 month to 18 years who have neurological disorders like epilepsy, migraine, or stroke. Researchers will use echocardiograms and ECGs to check for hidden heart problems. The goal is to understand if heart issues are common in these children an…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:21 UTC