Neuromuscular junction disease
MONDO:0020124Conditions characterized by impaired transmission of impulses at the neuromuscular junction. This may result from disorders that affect receptor function, pre- or postsynaptic membrane function, or acetylcholinesterase activity. The majority of diseases in this category are associated with autoimmune, toxic, or inherited conditions.
6 clinical trials for this condition and its sub-types, 1 tagged with Neuromuscular junction disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Neuromuscular junction disease
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Congenital myasthenic syndrome 5 trials
8 sub-types
- Postsynaptic congenital myasthenic syndrome 0 trials · 2 incl. sub-types Sub-types →
- Presynaptic congenital myasthenic syndrome 0 trials · 1 incl. sub-types Sub-types →
- Congenital myasthenic syndrome 15 0 trials
- Congenital myasthenic syndrome 5 0 trials
- Congenital myasthenic syndrome with tubular aggregates 0 trials Sub-types →
- Myasthenia, congenital, refractory to acetylcholinesterase inhibitors 0 trials
- Myasthenic syndrome, congenital, 22 0 trials
- Myasthenic syndrome, congenital, 7B, presynaptic, autosomal recessive 0 trials
Most studied deeper sub-types
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Nasal spray made from stem cells could help rare muscle condition
Disease control Recruiting nowThis early-stage trial is testing a nasal spray made from stem cell exosomes in 20 people with congenital myasthenic syndrome, a rare genetic condition that causes muscle weakness. The goal is to see if the treatment is safe and can improve oxygen levels. Because it is a Phase 1 …
Phase 1 • Sponsor: The Foundation for Orthopaedics and Regenerative Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can tracking daily life unlock myasthenia gravis mysteries?
Knowledge-focused Recruiting nowThis registry study follows adults with myasthenia gravis (MG) over time to understand how symptoms, daily functioning, and quality of life change. Participants complete surveys about their symptoms, treatments, and challenges, and may share medical records. The goal is to gather…
Sponsor: Autoimmune Neurology Alliance • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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New study tracks rare muscle disorders to improve future care
Knowledge-focused Recruiting nowThis study follows 75 people aged 6 months or older with congenital myasthenic syndromes (CMS), a group of inherited disorders that weaken communication between nerves and muscles. Over up to 7 visits in 5 years, researchers will use physical exams, heart and lung tests, MRIs, an…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Researchers track rare muscle disease to uncover its secrets
Knowledge-focused Recruiting nowThis study is for people with a rare genetic muscle condition called congenital myasthenic syndrome (CMS). It does not test any new drug or treatment. Instead, researchers will collect information from up to 100 participants over 4 visits to better understand how the disease affe…
Sponsor: argenx • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC