Jaw fracture

This trial compares two ways to humidify air for trauma patients on prolonged mechanical ventilation: active heated humidifiers and passive heat-and-moisture exchangers. The goal is to see which method reduces airway complications like mucus plugs and tube blockages, and improves…

This study tests whether stem cells taken from a patient's own belly fat can improve bone healing after surgery for a broken jaw. Twenty adults with jaw fractures will either get standard surgery plus stem cells or standard surgery alone. Researchers will check bone density and c…

This study tests whether a new shelf-stable blood product (IFC) works faster than the standard cryoprecipitate to stop severe bleeding in trauma patients. About 320 adults with traumatic injuries and low fibrinogen levels will be enrolled. The goal is to see if IFC can be given m…

This study looks at whether applying a patient's own skin cells (called a basal cell suspension) to surgical wounds can help them heal faster and with less scarring. Researchers will compare 500 people who get this extra treatment with 500 who get standard surgery alone. The goal…

This study is testing whether adding a cold atmospheric plasma device to standard wound care helps different types of wounds heal better. The device uses low-temperature plasma to kill bacteria and promote healing. Researchers will compare 500 patients who get plasma therapy plus…

This study tests whether custom-made 3D plates are better than standard titanium plates for fixing a specific type of jaw fracture (sub-condylar fracture). About 30 adults aged 18-60 with recent, displaced fractures will be randomly assigned to receive either a custom plate or a …

This study will compare two surgical techniques for fixing specific types of fractures in the roof of the mouth (palate). Forty patients will be randomly assigned to receive either a miniplate or a wire stabilization procedure. The main goals are to see which method better restor…

This study tests whether using a 3D-printed surgical guide and pre-bent metal plates can make jaw fracture surgery more accurate than the standard approach. Twenty adults with a specific type of jaw fracture will be randomly assigned to either the new precision method or the usua…

This study asks whether a simple ultrasound scan can safely and accurately track how well a child's broken bone is healing, compared with the standard X-ray. Children with fractures often need several X-rays during recovery, exposing them to small amounts of radiation. The trial …

This study tests whether an AI software called RBfracture helps clinicians better identify fractures, dislocations, and joint fluid buildup on X-rays. Sixteen doctors will review X-rays from 415 adult patients with and without the AI's help. The goal is to see if the AI improves …

This study tests whether a higher dose of the blood thinner enoxaparin can better prevent dangerous blood clots in the legs or lungs of severely injured patients. About 540 adults in intensive care after trauma will receive either the standard or a double dose. The goal is to see…

Researchers at the University of Alabama at Birmingham are testing whether a ketogenic tube feeding, high in fat and low in carbohydrates, is safe and practical for adults aged 55 and older hospitalized with traumatic injuries. They compare it with standard hospital tube feeding …

Researchers compare two surgical methods for fixing fractures in the front of the lower jaw: second-generation Herbert screws and 3-dimensional miniplates. The trial enrolls adults with recent anterior mandibular fractures who need surgery. The main measure is bone density around…

Researchers compare two surgical methods for repairing fractures in the front of the lower jaw: conventional plates and screws, or headless compression screws. Adults with a recent single fracture of the front jaw that needs surgery take part. The team uses imaging to measure the…

This trial tests whether using a weighted blanket during a hospital stay can reduce pain and anxiety in adults recovering from traumatic injuries. Half of the 50 participants will receive a weighted blanket, while the other half gets a standard hospital blanket. Researchers will …

This study will compare two pain medications, buprenorphine and oxycodone, in about 282 adults with injuries to at least two body areas. The goal is to see which provides better pain control with fewer risks. Participants will receive one of the two drugs as part of a standard pa…

This study tests whether listening to music with binaural beats (a type of sound that may influence brain activity) can help professional athletes who are afraid of getting hurt again after a musculoskeletal injury. Sixty-six athletes will listen to either binaural beat music, a …

This study tests whether applying platelet-rich fibrin (PRF) — a concentrate made from a patient's own blood — to the mental nerve during jaw fracture surgery can improve recovery of sensation in the chin and lower lip. 40 people with a broken jaw and numbness will be randomly as…

This study looks at whether giving trauma patients personalized information and a voluntary digital follow-up visit (instead of only standard care) helps them have less disability, return to work more often, and feel better overall. About 256 adults admitted to a Norwegian trauma…

Researchers at Assiut University Hospitals are reviewing medical records of patients treated for facial fractures between January 2025 and December 2028. The study aims to describe who gets these injuries, what caused them, which bones break, and how patients fare. By analyzing e…

Researchers at Radboud University Medical Center are asking what adults with serious trauma injuries and financial concerns need from physical therapy. The study includes 17 people in the Netherlands who were injured between three months and two years earlier. Through interviews,…

Researchers are studying whether adding the FOUR Score, a detailed measure of consciousness, to four existing trauma scoring systems improves their ability to predict death in adult trauma patients. The study enrolls about 2,000 injured adults across multiple hospitals. Participa…

Researchers want to understand what concerns trauma patients most right after an injury. The study enrolls 300 adults who arrive at the emergency department with an acute injury and are stable enough to take part. Participants fill out a questionnaire about their stress, pain, an…

This observational study aims to build and test models that predict risks like delirium and death after fracture surgery in older adults. Researchers will collect data on pain, sleep quality, and brain activity to see how these factors relate to short- and long-term outcomes. The…

This study watches 250 adults with broken leg or pelvis bones to see who develops hemorrhagic shock — a dangerous drop in blood pressure from blood loss. Researchers want to know which fractures are most likely to cause this emergency. The goal is to help doctors quickly spot and…

This study investigates why some people who have surgery for broken bones go on to develop long-term pain. Researchers are collecting blood samples and information on medical, psychological, and social factors from 600 adult patients. The goal is to create a model that can predic…

This trial tests a software device called AI-TRiPS that uses real-time data from ambulances to predict the risk of death, bleeding, kidney injury, and need for blood transfusion in trauma patients. The tool displays these predictions to hospital trauma teams before the patient ar…

This study will train over 1,800 lay first responders—like taxi drivers and shopkeepers—in Cameroon to provide basic first aid and safe transport for injured people. Researchers will compare survival rates before and after the training program. The goal is to see if a data-driven…

This study will test a new program designed to help people who have been hospitalized for a physical injury. The program connects survivors with resources to meet their medical and social needs. Researchers will interview 25 participants and track which resources they use to see …

This observational study will use a non-invasive brain-computer interface and artificial intelligence to detect and record brain activity in terminally ill patients immediately after clinical death. Researchers aim to capture organized neurocognitive signals, such as gamma waves,…

This study looks at 400 severely injured patients treated by emergency medical teams in the Paris region. It aims to see if the time spent on scene before going to the hospital affects whether patients survive the first 24 hours. The goal is to find ways to improve emergency care…

This study will analyze data from a pediatric trauma registry to understand injury patterns, outcomes, and what factors predict how severe an injury is. Researchers will look at records of 40 children under 18 who came to the hospital with a traumatic injury. The goal is to learn…

This study tests whether giving metoclopramide alone or with dexamethasone can speed up stomach emptying in trauma patients needing emergency surgery. Using bedside ultrasound, researchers will measure stomach contents to see which drug works better. The goal is to reduce the ris…

This study tests a new peer support program for adults recovering from serious injuries like car crashes, burns, or amputations. The program pairs survivors with trained peers who have been through similar experiences, offering support from hospital to home. The goal is to see if…

This study will look back at the medical records of about 2000 older adults (60+) who had surgery for a broken bone in Shanghai between 2010 and 2019. Researchers want to see how factors like age, nutrition, and which bone broke affect the risk of dying within 1, 3, or 5 years af…