Scientists to scan dying brains for hidden signals of consciousness
NCT ID NCT07477028
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study will use a non-invasive brain-computer interface and artificial intelligence to detect and record brain activity in terminally ill patients immediately after clinical death. Researchers aim to capture organized neurocognitive signals, such as gamma waves, that may occur during the transition from clinical to cellular death. The study will enroll 20 adults with a do-not-resuscitate order and expected survival of 7 days or less.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could provide the first scientific evidence of organized brain activity after clinical death, potentially reshaping our understanding of consciousness and near-death experiences.
- What could go wrong
- This is a very early feasibility study with only 20 participants. It may fail to detect clear signals due to noise or rapid brain deterioration, and results may not generalize to broader populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2035
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults (≥18 years) with terminal illness or severe acute trauma who have a do-not-resuscitate (DNR/DNI) order and for whom a legally authorized surrogate has provided informed consent. Participants are recruited from hospice, palliative care units, and intensive care units at three U.S. academic medical centers. The study focuses on individuals with physician-estimated survival of 7 days or less. All participants receive continuous non-invasive EEG/BCI monitoring during the peri-death period.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adults ≥18 years with terminal illness or severe acute trauma 2. Do-not-resuscitate (DNR/DNI) order in place 3. Surrogate decision-maker available and willing to provide informed consent 4. Expected survival ≤7 days (physician estimate) Exclusion Criteria: 1. Brain death already declared \> 24 hours prior to enrollment 2. Contraindication to EEG/BCI headset placement (e.g., severe scalp injury) 3. Patient lacks a legally authorized representative
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
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