Inflammation of heart layer
MONDO:0024636An inflammatory disease involving a pathogenic inflammatory response in the heart layer.
Also known as: carditis, heart layer inflammation
114 clinical trials for this condition and its sub-types, 1 tagged with Inflammation of heart layer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Inflammation of heart layer
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Endocarditis 51 trials · 61 incl. sub-types
3 sub-types
- Infective endocarditis 46 trials · 52 incl. sub-types Sub-types →
- Libman-Sacks endocarditis 0 trials
- Marantic endocarditis 0 trials
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Myocarditis 40 trials · 52 incl. sub-types
7 sub-types
- Acute myocarditis 15 trials · 16 incl. sub-types Sub-types →
- Bacterial myocarditis 2 trials Sub-types →
- Viral myocarditis 2 trials
- Fiedler's myocarditis 0 trials
- Autoimmune myocarditis 0 trials
- Interstitial myocarditis 0 trials
- Rheumatic myocarditis 0 trials
Most studied deeper sub-types
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Could less be more? major trial questions routine antibiotic for heart valve infections
Disease control Stopped earlyThis study looks at 330 adults with a serious heart valve infection (prosthetic valve endocarditis) caused by S. aureus bacteria. It compares the standard approach of giving the antibiotic rifampin against not giving it, to see if skipping it is just as safe and effective. The go…
Phase 3 • Sponsor: Todd C. Lee MD MPH FIDSA • Aim: Disease control
Last updated Sep 21, 2026 20:00 UTC
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Shorter antibiotic course after heart surgery for IV drug users shows promise
Disease control Stopped earlyThis study looked at whether people who had heart surgery for endocarditis (a serious heart infection) related to IV drug use could safely switch from IV antibiotics to oral pills after just two weeks. The goal was to see if this shorter hospital stay was safe and effective. The …
Phase 4 • Sponsor: West Virginia University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can a PET scan spot silent heart danger from cancer drugs?
Diagnosis Stopped earlyThis pilot study tested whether a special PET scan (FDG-PET/CT) can detect hidden heart inflammation in cancer patients receiving immune checkpoint inhibitors (ICIs). The goal was to catch this inflammation early, before it becomes severe. Only 2 participants were enrolled, and t…
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 12:31 UTC
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Exercise and diet boost mental health in heart infection patients
Symptom relief Stopped earlyThis study tested whether adding physical rehabilitation and personalized nutrition to standard care helps patients with infective endocarditis (a serious heart infection) feel better during their hospital stay. The goal was to improve mental health and quality of life. The study…
Sponsor: Johannes Grand • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC