Indeterminate colitis

This study tests whether oral vancomycin, an antibiotic, can help children aged 6-15 with inflammatory bowel disease (IBD), especially types linked to liver problems. About 140 kids will either get vancomycin plus standard care or standard care alone for up to a year. Researchers…

This early-phase study tests a new treatment called ICG318 CAR-T for people with inflammatory bowel disease (IBD) that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and calm the overactive immune response cau…

This study tests if xylitol, a common sweetener, can safely clear C. difficile bacteria from the gut in people with inflammatory bowel disease (IBD). About 99 adults with mild or inactive IBD will take either a low or high dose of xylitol or a placebo for four weeks. Researchers …

This study tests whether neurofeedback — a type of brain training using real-time brainwave feedback — can reduce musculoskeletal pain in people with chronic inflammatory bowel disease (IBD). Eighty adults with IBD and persistent pain will be randomly assigned to either 8 session…

Researchers are observing 300 adults aged 60 and older with inflammatory bowel disease who are starting an advanced therapy chosen by their usual care team. The study tracks immune-aging markers such as CD4/CD8 ratio and IL-6, along with frailty and nutrition, over 52 weeks. The …

Researchers at Assiut University Children Hospital are comparing conventional and biologic therapies in children and adolescents with inflammatory bowel disease, including Crohn's disease and ulcerative colitis. The study tracks about 100 patients to measure clinical remission at…

This study is exploring whether a rapid, non-invasive stool test can help monitor inflammatory bowel disease (IBD) in children. The test uses a technology called differential mobility spectrometry (DMS) to analyze the molecular profile of stool samples. Researchers will compare t…

This study follows 75 adults with Crohn's disease or ulcerative colitis who are starting guselkumab, a drug used for inflammatory bowel disease. Researchers want to see if the drug also helps with joint pain and stiffness linked to spondyloarthritis. Participants will report symp…

This study looks at a new way to control inflammation during flare-ups of Crohn's disease and ulcerative colitis. Researchers will take blood samples from 30 adults with severe IBD and test whether oxygen microbubbles can reprogram immune cells (monocytes) to produce fewer inflam…

This study will examine 100 patients with lower gut symptoms like chronic diarrhea, blood in stool, or abdominal pain who are having a colonoscopy. Researchers want to see which types of colon inflammation (colitis) are most common and how they appear during the procedure. The go…

This study looks at how weight and body mass index (BMI) change in people with inflammatory bowel disease (IBD) who are treated with biologic drugs. Researchers will track weight monthly and see if higher BMI leads to higher drug doses and costs. The goal is to understand the fin…

People with inflammatory bowel disease (IBD) have a higher risk of colon cancer and need regular colonoscopies. This study compares two advanced methods: one uses a dye spray to highlight abnormal areas, and the other uses built-in camera filters to enhance the view without dye. …

This study will follow 83 adults with inflammatory bowel disease (IBD) at Assiut University Hospitals in Egypt to see if anemia can predict worse outcomes like hospitalizations. Anemia is common in IBD, but its role as a predictor is not well studied in this population. Researche…

This study looks at how obesity influences treatment response in 120 adults with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will track whether obese patients respond differently to standard therapies, especially biologics. The …

This study will check if certain blood cell measurements (platelet count, size, and shape) are linked to how active inflammatory bowel disease (IBD) is. Researchers will compare these blood test results with standard disease activity scores in 84 adults with IBD. The goal is to s…

This study will check how common Helicobacter pylori infection is in 100 adults with inflammatory bowel disease (Crohn's or colitis) at the Guadeloupe hospital. Researchers will take extra stomach biopsies during routine endoscopy to study the stomach's bacteria. The goal is to s…

This study compares a newer imaging method called TXI with standard dye-based imaging during colonoscopies in people with inflammatory bowel disease (IBD). The goal is to see which method better detects precancerous changes that can lead to bowel cancer. About 242 adults with IBD…

This study will use a detailed heart ultrasound technique called speckle tracking to look for early signs of heart trouble in 100 adults with inflammatory bowel disease (IBD). Researchers want to see if this method can catch heart changes before they become serious and how those …

This study tests whether data from a wearable device and grocery loyalty cards can help detect disease flares in people with Crohn's disease or ulcerative colitis. Eighty adults will wear a smartwatch and use a store card to track their health and food purchases. The goal is to d…