Idiopathic scoliosis

Researchers are testing whether a short daily routine of one or two yoga poses can reduce spinal curvature in children aged 8 to 12 with juvenile idiopathic lumbar scoliosis. Participants practice the poses for 5 to 7 minutes, three times a day, for four months. Some children sta…

This trial tests three conservative approaches for adolescents with idiopathic scoliosis, a spine curvature that develops in childhood. Researchers compare a hypercorrective night-time brace worn for 8 hours, scoliosis-specific exercises, and general physical activity to see whic…

This trial is testing whether a person's genetic makeup can predict how well they respond to three common pain treatments: low-level laser therapy, therapeutic ultrasound, and prolotherapy (a dextrose injection). Researchers will recruit 80 people with myofascial pain and 80 with…

This trial tests whether adding pelvic floor muscle training to standard scoliosis-specific exercises can better reduce spine curvature in adolescents with idiopathic scoliosis. Participants aged 10-18 with mild to moderate curves will be randomly assigned to either exercises alo…

This trial tests whether a structured 16-week corrective exercise program can improve spinal alignment in adolescents aged 10–18 with mild to moderate scoliosis (Cobb angle 10°–40°). Participants are randomly assigned to either the corrective program or standard physiotherapy. Th…

This study tests a device called the Zimmer Biomet Tether System, which is surgically placed along the spine to correct curvature in children with scoliosis. Unlike traditional spinal fusion, which permanently joins vertebrae, this tethering approach aims to guide growth while pr…

This study tests whether a smartphone app that uses artificial intelligence can help teens with scoliosis do better exercises than traditional physical therapy. The app analyzes posture and creates a personalized workout plan. Researchers will compare spine curve changes and how …

This study compares two treatments—casting and bracing—for children under 3 with early-onset scoliosis. The goal is to see which method better controls spine curvature and improves quality of life. About 71 children and their parents are taking part.

This study tests a spine surgery for 20 teenagers (ages 12-21) with a specific type of scoliosis called Lenke 1. The goal is to correct the spine curve and improve quality of life. Researchers will measure how well the surgery works using X-rays and patient questionnaires.

This study was designed to test a device called the Globus Reflect Tether for children and teens with scoliosis who are still growing. The device is surgically attached to the spine to hold the curve in place, allowing the other side to grow and gradually straighten the spine. Th…

This study follows 200 teens with scoliosis who received the MID-C implant, a device that acts like an internal brace to straighten the spine. Researchers will check if the spine stays corrected (curvature under 40 degrees) and monitor for any safety issues over 5 years. The goal…

This study tests a 3D body scanner called NSite to see if it can reliably monitor scoliosis in teenagers. Thirteen teens with scoliosis will be scanned by three different users to check if the results are consistent. If it works, this device could offer a radiation-free way to tr…

This study looks at whether adding a low-dose dexmedetomidine infusion to standard pain management can lower the amount of narcotics needed and reduce side effects like nausea and itching in teenagers having posterior spinal fusion for scoliosis. About 160 adolescents with idiopa…

This study looks at whether playing active video games can help teenagers regain balance and posture better than standard exercises after scoliosis surgery. About 51 teens who had spinal fusion will be split into three groups: video game training, standard stabilization exercises…

This study tests whether doing special flexibility exercises for 6 months before spinal fusion surgery helps teens with scoliosis. Researchers want to see if it leads to fusing fewer vertebrae, better curve correction, shorter surgery, and less time in the hospital. Forty teens a…

This study compares a new opioid-free pain management plan to the usual opioid-based approach for teenagers (ages 10-20) having spinal fusion surgery for scoliosis. The opioid-free plan uses a mix of numbing injections and non-opioid medications like gabapentin, ibuprofen, and ac…

Researchers are reviewing past spinal fusion surgeries to see if patient-specific guides, called MySpine, place screws safely even in the most challenging bone. They will compare nerve irritation rates between standard screws and those in anatomically complex positions, known as …

This study tests whether a special type of X-ray called DXA, taken while lying down, can measure spine curves as well as standard standing X-rays in people with scoliosis. About 20 participants will have both types of images taken, and researchers will compare the results and ask…

This study aims to develop a new way to measure how the spine moves during walking in children, both healthy and those with scoliosis. Researchers will use a special camera system and reflective markers placed on the skin to track movement. The goal is to create a reliable and ea…

This study follows nearly 2,000 adults with spinal deformity (curved spine) to compare outcomes between those who have surgery and those who do not. Researchers track X-rays, pain levels, and quality of life over time. The goal is to learn which approach leads to better long-term…

This study looks at whether sleep-disordered breathing, like obstructive sleep apnea, is linked to worsening spine curves in children with idiopathic scoliosis. Researchers will follow 405 children aged 6 to 15 with mild to moderate scoliosis. They will measure spine curves and s…

This study looks at how the way the lower back and pelvis move together (lumbopelvic rhythm) impacts balance, daily activities, and quality of life in 50 adolescents aged 10-18 with idiopathic scoliosis. Researchers will use motion sensors and balance platforms to measure these m…

This study tests a computer program designed to help doctors choose the best rehabilitation plan for teens with idiopathic scoliosis. Doctors will first make treatment decisions as usual, then see what the computer suggests for the same patients three months later. The goal is to…

This study was designed to see if a special saltwater solution (buffered 2% hypertonic saline) is better than standard fluids for children and teens having spine surgery for scoliosis. The goal was to compare how the body's acid-base balance and electrolyte levels changed during …

This study tests whether a single session of a self-corrective exercise can immediately improve muscle activity and spinal alignment in 40 adolescents with idiopathic scoliosis. Participants do both a standard exercise and the self-corrective exercise, and researchers measure cha…

This study looks at how a child's genes and emotions influence pain after major spine surgery. Researchers will follow 880 teens aged 10-18 having spine fusion for scoliosis or similar conditions. They will measure pain levels, breathing problems, and nausea after surgery, and ch…

This study looks at 84 teens with scoliosis to see if the way they put pressure on their feet is linked to the shape of their spine curve. Participants simply stand on a pressure-sensing mat while doctors also check their spine X-rays. The goal is to better understand how scolios…