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Targeted exercise may straighten spines in teens with scoliosis — a trial puts it to the test

NCT ID NCT07736456

Disease control Sponsor: Alma Mater Europaea - Slovenia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether a structured 16-week corrective exercise program can improve spinal alignment in adolescents aged 10–18 with mild to moderate scoliosis (Cobb angle 10°–40°). Participants are randomly assigned to either the corrective program or standard physiotherapy. The study measures changes in spinal curvature, rotation, and pelvic position using 3D imaging, along with quality of life. The goal is to see if a targeted exercise approach offers better results than routine care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a structured physiotherapeutic corrective exercise program including core stabilization, stretching, spine autocorrection, and pelvic stabilization exercises
What this could lead to
If effective, this program could offer a non-surgical way to slow or improve spinal curvature in adolescents with scoliosis, potentially reducing the need for bracing or surgery.
What could go wrong
This is a relatively small trial (68 participants) testing a 16-week program, so results may not apply to all cases. Exercise requires consistent effort, and benefits may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 68 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adolescents aged 10 to 18 years. * Diagnosis of mild to moderate adolescent idiopathic scoliosis (AIS) with a Cobb angle between 10° and 40°. * Referred for physiotherapy treatment at the Physical Medicine and Rehabilitation Clinic. * Ability to participate in a 16-week exercise program. * Written informed consent from a parent or legal guardian and assent from the participant. * Agreement not to receive additional scoliosis-specific treatment during the study period. Exclusion Criteria: * Non-idiopathic scoliosis (congenital, neuromuscular, or syndromic scoliosis). * Cervicothoracic scoliosis. * Previous scoliosis surgery. * Brace treatment during the study period. * Previous scoliosis-specific physiotherapy during the study period. * Neurological disorders affecting posture or gait. * Congenital or structural spinal abnormalities. * Lower extremity neuromuscular disorders. * Leg length discrepancy. * Cardiovascular or respiratory conditions contraindicating exercise. * Inability to participate in the intervention or complete outcome assessments.

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Conditions

The condition(s) this trial relates to.

adolescent idiopathic scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Scoliosis idiopathic adolescent

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Physical Medicine and Rehabilitation Clinic, University Clinical Center of Kosovo (UCCK)

    Pristina, Kosovo, 10000, Kosovo

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