Hypothyroidism

This study asks whether adults aged 65 and older with mild underactive thyroid (subclinical hypothyroidism) can safely stop their low-dose levothyroxine medication. Half the participants will continue their usual levothyroxine, while the other half will receive a placebo for 6 mo…

This study tests whether a smartphone app and text reminders can help people with hypothyroidism take their thyroid medication more regularly. The goal is to see if better medication adherence reduces fatigue, helps with weight management, and improves thyroid hormone levels. The…

This study tests whether adding a second thyroid hormone (T3) to the standard T4 treatment can improve persistent symptoms like fatigue and brain fog in people with hypothyroidism. It involves 60 adults aged 18-70 who still have symptoms despite normal thyroid blood tests. Partic…

This study tests whether a structured 12-week walking program can improve metabolism, reduce fatigue, and lower stress in women with hypothyroidism who are already on thyroid medication. 120 women aged 35-55 will either walk 30 minutes, 5 times a week under supervision, or contin…

Researchers at Assiut University are studying whether an underactive thyroid makes liver scarring worse in people with metabolic dysfunction-associated steatotic liver disease (MASLD). The trial enrolls 120 adults with MASLD, half of whom have overt or subclinical hypothyroidism …

Researchers are measuring how often subclinical hypothyroidism, a mild form of underactive thyroid, occurs in people with rheumatoid arthritis compared to healthy people. They will also check whether this thyroid condition relates to higher disease activity or more severe joint i…

This study looks at whether an underactive thyroid (hypothyroidism) is linked to more severe liver scarring in people with metabolic dysfunction-associated steatotic liver disease (MASLD). Researchers will compare two groups of adults with MASLD: those with hypothyroidism and tho…

This study looks at how anticipated stigma and illness identity affect quality of life in men with hypogonadism (low testosterone). It compares these men to those with other chronic endocrine conditions like diabetes, hypothyroidism, or hypertension. The goal is to see if these p…

This study will check if doing two blood tests instead of one can better detect congenital hypothyroidism in premature babies born before 32 weeks. Researchers will follow 1,600 newborns in France, testing them within 15 days of birth and again at 2 years if needed. The goal is t…

This study will use ultrasound to measure the thyroid gland in 400 healthy full-term newborns in Italy. The goal is to create a set of normal thyroid volume values, which currently do not exist for this population. These reference values can help doctors better diagnose thyroid p…

This study looks at whether a mild form of underactive thyroid (subclinical hypothyroidism) affects liver enzymes and cholesterol levels. Researchers will compare 120 adults with and without the condition. No treatment is given — the goal is simply to understand the connection be…