Please sign in to follow a disease.

Isolated thyrotropin-releasing hormone deficiency

MONDO:0010140

Hypothyroidism due to dysfunction of the hypothalamus, assumed to result in reduced secretion of thyrotropin- releasing hormone.

Also known as: isolated TRF deficiency, isolated TRH deficiency, isolated TSH-releasing factor deficiency, isolated prothyroliberin deficiency, isolated protirelin deficiency, isolated thyroliberin deficiency, isolated thyrotropin-releasing factor deficiency, tertiary hypothyroidism

1 clinical trial for this condition and its sub-types, 0 tagged with Isolated thyrotropin-releasing hormone deficiency itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Central congenital hypothyroidism (2)

Including sub-types (1) Tagged with Isolated thyrotropin-releasing hormone deficiency (0)

Trials to join now! 1

Scientists watch thyroid conditions unfold in 2,500 patients

Knowledge-focused Recruiting now

This study follows up to 2,500 people with thyroid problems like hyperthyroidism, hypothyroidism, or Graves' disease. Researchers will track how these conditions develop over time using standard medical tests and genetic samples. The goal is to better understand the natural histo…

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused

Last updated Sep 18, 2026 00:00 UTC

Isolated thyrotropin-releasing hormone deficiency

Where it sits in the disease tree

Scientists watch thyroid conditions unfold in 2,500 patients