Hidden thyroid problem could silently harm liver and cholesterol
NCT ID NCT07236697
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a mild form of underactive thyroid (subclinical hypothyroidism) affects liver enzymes and cholesterol levels. Researchers will compare 120 adults with and without the condition. No treatment is given — the goal is simply to understand the connection better.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
internal medicine department
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Age ≥ 18 years * For SCH group: Elevated TSH with normal FT4 * For control group: Normal TSH and FT4 levels Exclusion Criteria: * • Evident hypothyroidism or hyperthyroidism * Diagnosed with diabetes mellitus * Chronic liver disease * Chronic kidney disease * Use of lipid-lowering or thyroid medications * Pregnancy * Alcohol abuse
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Assiut university hospitals
Asyut, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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