Hereditary neoplastic syndrome

MONDO:0015356

The inherited predisposition toward getting a tumor.

Also known as: cancer syndrome, hereditary, cancer syndromes, hereditary, familial neoplastic syndrome, familial tumor syndrome, familial tumour syndrome, hereditary cancer syndrome, hereditary cancer syndromes, hereditary neoplastic syndrome

734 clinical trials for this condition and its sub-types, 60 tagged with Hereditary neoplastic syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disease (18235) ↑ Neoplastic syndrome (1432) ↑ Inherited disease susceptibility (1316)

Sub-types of Hereditary neoplastic syndrome

Glioma susceptibility 0 trials · 133 incl. sub-types
10 sub-types
- Glioma susceptibility 1 133 trials
- Glioma susceptibility 2 0 trials
- Glioma susceptibility 3 0 trials
- Glioma susceptibility 4 0 trials
- Glioma susceptibility 5 0 trials
- Glioma susceptibility 6 0 trials
- Glioma susceptibility 7 0 trials
- Glioma susceptibility 8 0 trials
- Melanoma, cutaneous malignant, susceptibility to, 9 0 trials
- Tumor predisposition syndrome 3 0 trials
Neurofibromatosis 19 trials · 94 incl. sub-types
5 sub-types
- Neurofibromatosis type 1 73 trials Sub-types →
- NF2-related schwannomatosis 21 trials
- Schwannomatosis 3 trials Sub-types →
- Neurofibromatosis-Noonan syndrome 2 trials Sub-types →
- Neurofibromatosis, type IV, of Riccardi 0 trials
Hereditary nonpolyposis colon cancer 5 trials · 88 incl. sub-types
5 sub-types
- Lynch syndrome 81 trials · 83 incl. sub-types Sub-types →
- Muir-Torre syndrome 2 trials
- Colorectal cancer, hereditary nonpolyposis, type 6 1 trial
- Colorectal cancer, hereditary nonpolyposis, type 7 0 trials
- Familial colorectal cancer type X 0 trials
Multiple endocrine neoplasia 7 trials · 62 incl. sub-types
3 sub-types
- Multiple endocrine neoplasia type 1 34 trials
- Multiple endocrine neoplasia type 2 4 trials · 30 incl. sub-types Sub-types →
- Multiple endocrine neoplasia type 4 0 trials
Intestinal polyposis syndrome 3 trials · 53 incl. sub-types
8 sub-types
- Classic or attenuated familial adenomatous polyposis 0 trials · 35 incl. sub-types Sub-types →
- Peutz-Jeghers syndrome 9 trials
- Hereditary mixed polyposis syndrome 5 trials · 6 incl. sub-types Sub-types →
- Juvenile polyposis syndrome 5 trials Sub-types →
- Bannayan-Riley-Ruvalcaba syndrome 1 trial
- Cronkhite-Canada syndrome 1 trial
- Hyperplastic polyposis syndrome 1 trial Sub-types →
- Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome 0 trials
Tuberous sclerosis 41 trials · 44 incl. sub-types
2 sub-types
- Tuberous sclerosis 1 33 trials
- Tuberous sclerosis 2 2 trials
Leukemia, acute lymphocytic, susceptibility to, 1 41 trials
BRCA2-related cancer predisposition 36 trials · 38 incl. sub-types
3 sub-types
- Breast-ovarian cancer, familial, susceptibility to, 2 2 trials
- Glioma susceptibility 3 0 trials
- Pancreatic cancer, susceptibility to, 2 0 trials
Hereditary breast ovarian cancer syndrome 35 trials · 38 incl. sub-types
2 sub-types
- Breast-ovarian cancer, familial, susceptibility to, 1 3 trials
- Breast-ovarian cancer, familial, susceptibility to, 2 2 trials
Mismatch repair cancer syndrome 1 34 trials
BRCA1-related cancer predisposition 23 trials · 27 incl. sub-types
2 sub-types
- Breast-ovarian cancer, familial, susceptibility to, 1 3 trials
- Pancreatic cancer, susceptibility to, 4 1 trial
Nasopharyngeal carcinoma, susceptibility to, 1 21 trials
Li-Fraumeni syndrome 16 trials
PALB2-related cancer predisposition 14 trials
1 sub-type
- Pancreatic cancer, susceptibility to, 3 0 trials
Dyskeratosis congenita 12 trials
16 sub-types
- DKC1-related disorder 0 trials · 3 incl. sub-types Sub-types →
- Revesz syndrome 2 trials
- Dyskeratosis congenita and related telomere biology disorder 1 trial Sub-types →
- Autosomal recessive dyskeratosis congenita 4 0 trials
- Dyskeratosis congenita, autosomal dominant 1 0 trials
- Dyskeratosis congenita, autosomal dominant 2 0 trials
- Dyskeratosis congenita, autosomal dominant 3 0 trials
- Dyskeratosis congenita, autosomal dominant 4 0 trials
- Dyskeratosis congenita, autosomal dominant 6 0 trials
- Dyskeratosis congenita, autosomal recessive 1 0 trials
- Dyskeratosis congenita, autosomal recessive 2 0 trials
- Dyskeratosis congenita, autosomal recessive 3 0 trials
- Dyskeratosis congenita, autosomal recessive 6 0 trials
- Dyskeratosis congenita, autosomal recessive 7 0 trials
- Dyskeratosis congenita, autosomal recessive 8 0 trials
- Dyskeratosis congenita, digenic 0 trials
Wiskott-Aldrich syndrome 10 trials
Hereditary leiomyomatosis and renal cell cancer 8 trials
PTEN hamartoma tumor syndrome 6 trials · 8 incl. sub-types
4 sub-types
- Proteus syndrome 2 trials
- Bannayan-Riley-Ruvalcaba syndrome 1 trial
- Proteus-like syndrome 0 trials
- Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome 0 trials
CHEK2-related cancer predisposition 7 trials
Susceptibility to familial cutaneous melanoma 0 trials · 7 incl. sub-types
10 sub-types
- Melanoma, cutaneous malignant, susceptibility to, 2 6 trials
- Melanoma, cutaneous malignant, susceptibility to, 1 1 trial
- Melanoma, cutaneous malignant, susceptibility to, 3 0 trials
- Melanoma, cutaneous malignant, susceptibility to, 4 0 trials
- Melanoma, cutaneous malignant, susceptibility to, 5 0 trials
- Melanoma, cutaneous malignant, susceptibility to, 6 0 trials
- Melanoma, cutaneous malignant, susceptibility to, 7 0 trials
- Melanoma, cutaneous malignant, susceptibility to, 8 0 trials
- Melanoma, cutaneous malignant, susceptibility to, 9 0 trials
- Tumor predisposition syndrome 3 0 trials
BAP1-related tumor predisposition syndrome 6 trials
Beckwith-Wiedemann syndrome 6 trials
8 sub-types
- Beckwith-Wiedemann syndrome due to 11p15 microdeletion 0 trials
- Beckwith-Wiedemann syndrome due to 11p15 microduplication 0 trials
- Beckwith-Wiedemann syndrome due to 11p15 translocation/inversion 0 trials
- Beckwith-Wiedemann syndrome due to CDKN1C mutation 0 trials
- Beckwith-Wiedemann syndrome due to NSD1 mutation 0 trials
- Beckwith-Wiedemann syndrome due to imprinting defect of 11p15 0 trials
- Beckwith-Wiedemann syndrome due to paternal uniparental disomy of chromosome 11 0 trials
- Franceschini Vardeu Guala syndrome 0 trials
RAD51C-related cancer predisposition 6 trials
Hereditary pheochromocytoma-paraganglioma 6 trials
9 sub-types
- MAX-related tumor predisposition 0 trials
- TMEM127-related tumor predisposition 0 trials
- Pheochromocytoma/paraganglioma syndrome 1 0 trials
- Pheochromocytoma/paraganglioma syndrome 2 0 trials
- Pheochromocytoma/paraganglioma syndrome 3 0 trials
- Pheochromocytoma/paraganglioma syndrome 4 0 trials
- Pheochromocytoma/paraganglioma syndrome 5 0 trials
- Pheochromocytoma/paraganglioma syndrome 6 0 trials
- Pheochromocytoma/paraganglioma syndrome 7 0 trials
Nevoid basal cell carcinoma syndrome 5 trials
2 sub-types
- Basal cell nevus syndrome 1 0 trials
- Basal cell nevus syndrome 2 0 trials
Hereditary thrombocytopenia and hematologic cancer predisposition syndrome 1 trial · 5 incl. sub-types
2 sub-types
- Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with RUNX1 5 trials
- Thrombocytopenia 5 0 trials
RAD51D-related cancer predisposition 4 trials
Kostmann syndrome 3 trials
Li-fraumeni-like syndrome 3 trials
Familial atypical multiple mole melanoma syndrome 3 trials
1 sub-type
- Melanoma-pancreatic cancer syndrome 0 trials
Hereditary multiple osteochondromas 3 trials
3 sub-types
- Exostoses, multiple, type 1 2 trials
- Exostoses, multiple, type 2 0 trials
- Exostoses, multiple, type III 0 trials
BARD1-related cancer predisposition 2 trials
Maffucci syndrome 2 trials
Blue rubber bleb nevus 2 trials
Hereditary retinoblastoma 2 trials
Inherited hematologic cancer-predisposing syndrome 2 trials
Leukemia, chronic lymphocytic, susceptibility to, 2 2 trials
Neuroblastoma, susceptibility to, 3 2 trials
Brooke-Spiegler syndrome 0 trials · 2 incl. sub-types
2 sub-types
- Familial cylindromatosis 2 trials
- Familial multiple trichoepithelioma 0 trials Sub-types →
Rothmund-Thomson syndrome 1 trial
4 sub-types
- Rothmund-Thomson syndrome type 1 0 trials
- Rothmund-Thomson syndrome type 2 0 trials
- Rothmund-Thomson syndrome type 3 0 trials
- Rothmund-Thomson syndrome type 4 0 trials
SAMD9-related spectrum and myeloid neoplasm risk 1 trial
SAMD9L-related spectrum and myeloid neoplasm risk 1 trial
WAGR syndrome 1 trial
1 sub-type
- Wilms tumor, aniridia, genitourinary anomalies, intellectual disability, and obesity syndrome 0 trials
Cherubism 1 trial
1 sub-type
- Al Gazali Khidr Prem Chandran syndrome 0 trials
Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors 1 trial
Hyperparathyroidism 2 with jaw tumors 1 trial
Familial rhabdoid tumor 0 trials · 1 incl. sub-types
2 sub-types
- Rhabdoid tumor predisposition syndrome 2 1 trial
- Rhabdoid tumor predisposition syndrome 1 0 trials
ATM-related cancer predisposition 0 trials
CDH1-related diffuse gastric and lobular breast cancer syndrome 0 trials
Carney-Stratakis syndrome 0 trials
Cobb syndrome 0 trials
DDX41-related hematologic malignancy predisposition syndrome 0 trials
EGLN1-related erythrocytosis and pheochromocytoma/paraganglioma predisposition 0 trials
GPR161-related medulloblastoma predisposition 0 trials
HAVCR2-related cancer predisposition 0 trials
Kaposi sarcoma, susceptibility to 0 trials
N syndrome 0 trials
NTHL1-deficiency tumor predisposition syndrome 0 trials
Basal cell carcinoma, susceptibility to, 7 0 trials
Breast cancer, familial, susceptibility to, 1 0 trials
Breast cancer, familial, susceptibility to, 2 0 trials
Breast cancer, familial, susceptibility to, 3 0 trials
Cholangiocarcinoma, susceptibility to 0 trials
Colorectal cancer, susceptibility to, 1 0 trials
Colorectal cancer, susceptibility to, 10 0 trials
Colorectal cancer, susceptibility to, 11 0 trials
Colorectal cancer, susceptibility to, 12 0 trials
Colorectal cancer, susceptibility to, 2 0 trials
Colorectal cancer, susceptibility to, 3 0 trials
Colorectal cancer, susceptibility to, 4 0 trials
Colorectal cancer, susceptibility to, 5 0 trials
Colorectal cancer, susceptibility to, 6 0 trials
Colorectal cancer, susceptibility to, 7 0 trials
Colorectal cancer, susceptibility to, 8 0 trials
Colorectal cancer, susceptibility to, 9 0 trials
Colorectal cancer, susceptibility to, on chromosome 15 0 trials
Diffuse gastric and lobular breast cancer syndrome with or without cleft lip and/or palate 0 trials
Erythroleukemia, familial, susceptibility to 0 trials
Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome 0 trials
Familial isolated hyperparathyroidism 0 trials
3 sub-types
- Hyperparathyroidism 1 0 trials
- Hyperparathyroidism 3 0 trials
- Hyperparathyroidism 4 0 trials
Familial multiple fibrofolliculoma 0 trials
Follicular lymphoma, susceptibility to 0 trials
2 sub-types
- Follicular lymphoma, susceptibility to, 1 0 trials
- Follicular lymphoma, susceptibility to, 2 0 trials
Hemangioma, capillary infantile, susceptibility to 0 trials
Leukemia, acute lymphoblastic, susceptibility to, 3 0 trials
Leukemia, acute lymphocytic, susceptibility to, 2 0 trials
Leukemia, acute myeloid, susceptibility to 0 trials
Leukemia, chronic lymphocytic, susceptibility to, 1 0 trials
Leukemia, chronic lymphocytic, susceptibility to, 3 0 trials
Leukemia, chronic lymphocytic, susceptibility to, 4 0 trials
Leukemia, chronic lymphocytic, susceptibility to, 5 0 trials
Lung cancer susceptibility 1 0 trials
Lung cancer susceptibility 3 0 trials
Lung cancer susceptibility 4 0 trials
Lung cancer susceptibility 5 0 trials
Melanoma and neural system tumor syndrome 0 trials
Mosaic neurofibromatosis/schwannomatosis 0 trials
3 sub-types
- Mosaic NF2-related schwannomatosis 0 trials
- Mosaic neurofibromatosis type 1 0 trials
- Mosaic schwannomatosis 0 trials
Mosaic variegated aneuploidy syndrome 0 trials
7 sub-types
- Atelis syndrome 1 0 trials
- Atelis syndrome 2 0 trials
- Mosaic variegated aneuploidy syndrome 1 0 trials
- Mosaic variegated aneuploidy syndrome 2 0 trials
- Mosaic variegated aneuploidy syndrome 3 0 trials
- Mosaic variegated aneuploidy syndrome 4 0 trials
- Mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition 0 trials
Multiple self-healing squamous epithelioma 0 trials
Nasopharyngeal carcinoma, susceptibility to, 2 0 trials
Nasopharyngeal carcinoma, susceptibility to, 3 0 trials
Neuroblastoma, susceptibility to, 1 0 trials
Neuroblastoma, susceptibility to, 2 0 trials
Neuroblastoma, susceptibility to, 4 0 trials
Neuroblastoma, susceptibility to, 5 0 trials
Neuroblastoma, susceptibility to, 6 0 trials
Neuroblastoma, susceptibility to, 7 0 trials
Ovarian cancer, familial, susceptibility to, 1 0 trials
Ovarian cancer, familial, susceptibility to, 2 0 trials
Ovarian cancer, familial, susceptibility to, 3 0 trials
Ovarian cancer, susceptibility to, 1 0 trials
Pancreatic cancer, susceptibility to, 1 0 trials
Pancreatic cancer, susceptibility to, 5 0 trials
Progeroid features-hepatocellular carcinoma predisposition syndrome 0 trials
Prostate cancer, hereditary, X-linked 3 0 trials
Prostate cancer/brain cancer susceptibility 0 trials
Susceptibility to uveal melanoma 0 trials
2 sub-types
- Melanoma, uveal, susceptibility to, 1 0 trials
- Melanoma, uveal, susceptibility to, 2 0 trials
Tumor predisposition syndrome 2 0 trials

Most studied deeper sub-types

Classic familial adenomatous polyposis (33) Familial medullary thyroid carcinoma (23) Lynch syndrome 1 (5) Multiple endocrine neoplasia type 2A (4) Attenuated familial adenomatous polyposis (3) Hoyeraal-Hreidarsson syndrome (3) Lynch syndrome 2 (3) Familial adenomatous polyposis 1 (2) Multiple endocrine neoplasia type 2B (2) Polyposis syndrome, hereditary mixed, 1 (2) Colon serrated polyposis (1) Familial adenomatous polyposis 2 (1) Gardner syndrome (1) Polymerase proofreading-related adenomatous polyposis (1) 22q-related schwannomatosis (0) APC-related attenuated familial adenomatous polyposis (0) AXIN2-related attenuated familial adenomatous polyposis (0) BMPR1A-related juvenile polyposis syndrome (0) Chromosome 17q11.2 deletion syndrome, 1.4Mb (0) Dyskeratosis congenita, autosomal recessive 5 (0)

Including sub-types (734) Tagged with Hereditary neoplastic syndrome (60)

Trials to join now! 30 Not yet recruiting 6 Not yet finished but already full! 13 Completed 11

Hereditary neoplastic syndrome

Where it sits in the disease tree

Most studied deeper sub-types

Could pregnancy be the perfect time to screen for cancer genes?

Simple blood test aims to catch cancers early in genetically prone patients

Simple blood test could spot cancer earlier in High-Risk individuals

Urine DNA test could spot bladder cancer early in lynch syndrome patients

Scientists dig into why skin tumors grow in rare disease

The question after preventive mastectomy: would women do it again?

New study aims to catch mesothelioma early in High-Risk families

Scientists launch massive tumor repository to unlock cancer secrets

Scientists hunt for hidden cancer clues in families

Massive study aims to decode cancer genes for better family counseling

Scientists bank tumors and blood to unlock cancer secrets

Scientists hunt for hidden genes behind hereditary cancers

Free genetic testing offered to 27,500 people to find hidden cancer risks

Could a chatbot help close the gap in genetic cancer testing?

Hunt for hidden cancer genes: families needed to unlock hereditary secrets

Can young adults at genetic cancer risk keep up with checkups after pediatric care ends?

Can online tools boost genetic testing in families with hereditary cancer?

New questionnaire aims to catch hidden cancer genes in children

New study aims to unlock why lynch syndrome patients still get cancer despite surveillance

Can better conversations prevent cancer? new study investigates

Massive study aims to unlock secrets of rare Cancer-Predisposing gene

New study uses DNA tests to catch blood cancers before they start

Community clinics test smarter ways to spot cancer genes

Can a website replace the genetic counselor? new study tests online cancer risk testing

Can doctors help families unlock Life-Saving genetic secrets?

Could pregnancy checkups also screen for cancer genes?

Scientists hunt for hidden cancer genes in 1,500 patients

Chatbot aims to close genetic testing gap for black cancer survivors

New study tracks kids prone to cancer to uncover early warning signs

Scientists hunt for hidden genes behind rare tumors