Could pregnancy checkups also screen for cancer genes?
NCT ID NCT07052266
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether offering genetic testing for inherited cancer risk (like BRCA1/2) during routine pregnancy or fertility care is practical and acceptable to patients. Researchers will enroll 550 people receiving prenatal or preconception care at Weill Cornell Medicine. The goal is to see how many complete both standard prenatal genetic screening and the optional cancer risk screening, and to understand if this approach could help catch cancer risks earlier, especially in underserved groups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- MyRisk Hereditary Cancer Test (genetic screening)
- What this could lead to
- If successful, this could show that offering cancer genetic testing during pregnancy or fertility care is practical and welcomed, potentially leading to earlier cancer detection and prevention in a broader population.
- What could go wrong
- This is an early feasibility study, not a treatment trial. It measures interest and completion rates, not health outcomes. Results may not apply to all populations or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 550 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years - 55 years * Pregnant patients receiving obstetrical-related care or receiving preconception/fertility care at a WCM-affiliated enrollment site. * Patients who have elected to undergo OCS with the WCM-affiliated obstetrics provider * Patients with prior OCS but planned to repeat OCS are eligible * Patients can speak and read in English or Spanish Exclusion Criteria: * Patients who have previously completed a multigene hereditary cancer syndrome panel * Patients who have a hematologic cancer or hematologic pre-cancer * Patients who have a history of an autologous bone marrow transplant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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NewYork-Presbyterian Weill Cornell Medicine
NOT_YET_RECRUITINGBrooklyn, New York, 11215, United States
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NewYork-Presbyterian Weill Cornell Medicine Queens
RECRUITINGQueens, New York, 11355, United States
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Reproductive Medicine
RECRUITINGBrooklyn, New York, 11201, United States
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Reproductive Medicine
RECRUITINGNew York, New York, 10021, United States
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
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Other studies related to the condition(s) this trial covers.
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- Can an app keep young people with cancer genes on track?