Hereditary glaucoma
MONDO:0018174Hereditary glaucoma is a clinically diverse group of rare eye disorders with genetic predisposition characterized by elevated intraocular pressure (IOP) and glaucomatous changes of the optic nerve head, leading to field defects, visual loss and blindness. Hereditary glaucoma can be sub-classified as primary (congenital glaucoma, juvenile glaucoma) or secondary according to the presence or absence of systemic or other ocular anomalies (iridogoniodysgenesis, Stickler syndrome, Coats syndrome). The clinical presentation is variable and is based on age, severity of glaucoma, presence of ocular abnormalities and development of secondary IOP related abnormalities.
Also known as: hereditary glaucoma (disease), glaucoma, hereditary
55 clinical trials for this condition and its sub-types, 0 tagged with Hereditary glaucoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hereditary glaucoma
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Exfoliation syndrome 32 trials
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Juvenile open angle glaucoma 7 trials · 15 incl. sub-types
6 sub-types
- Glaucoma 1, open angle, l 8 trials
- Glaucoma 1, open angle, A 0 trials
- Glaucoma 1, open angle, J 0 trials
- Glaucoma 1, open angle, K 0 trials
- Glaucoma 1, open angle, M 0 trials
- Glaucoma 1, open angle, N 0 trials
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Congenital glaucoma 6 trials · 7 incl. sub-types
4 sub-types
- Primary congenital glaucoma 2 trials · 4 incl. sub-types Sub-types →
- Glaucoma 3, primary congenital, E 0 trials
- Glaucoma 3, primary infantile, B 0 trials
- Glaucoma type 1C 0 trials
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Anterior segment dysgenesis 3 1 trial
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Iris hypoplasia with glaucoma 1 trial
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OPTN-related open angle glaucoma 0 trials
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TEK-related primary glaucoma 0 trials
1 sub-type
- Glaucoma 3, primary congenital, E 0 trials
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Glaucoma 1, open angle, O 0 trials
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Glaucoma 1, open angle, P 0 trials
Most studied deeper sub-types
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Can a laser treat glaucoma without touching the eye?
Disease control CompletedThis pilot study tests a new laser device for treating open-angle glaucoma and ocular hypertension. The device uses a laser through the sclera (the white of the eye) to lower eye pressure, avoiding the need for a lens to touch the cornea. Researchers will check how safe the proce…
Sponsor: Lumibird Medical (Quantel Medical, Ellex Medical, Optotek) • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New surgical twist may save sight in babies with rare glaucoma
Disease control CompletedThis study looks at a modified surgical technique for children with primary congenital glaucoma, a condition that causes high eye pressure and can lead to blindness if untreated. The surgery combines two procedures to create a better drainage channel for fluid inside the eye. Res…
Sponsor: Benha University • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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New eye implant could reduce glaucoma drops
Disease control CompletedThis study tested a small implant called Supraflow v2.2 in 57 adults with open-angle or narrow-angle glaucoma. The implant is placed inside the eye to help drain fluid and lower eye pressure. The goal was to see if it safely reduces pressure and the need for daily eye drops over …
Sponsor: Ciliatech • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New 'Micro' eye surgery could ease glaucoma treatment
Disease control CompletedThis study tested a new, less invasive surgery called MIMS for people with glaucoma. The goal was to see if it lowers eye pressure as well as traditional surgery but with fewer side effects. 23 adults with glaucoma took part. The results will help doctors understand if MIMS is a …
Sponsor: Hôpital Privé de la Baie • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Can a new eye test match the gold standard for glaucoma?
Diagnosis CompletedThis study compares two visual field tests used to monitor glaucoma: the current standard Humphrey Visual Field Analyzer and the newer iCare COMPASS. About 28 people with glaucoma or related eye conditions will take both tests in the same visit, with the order alternating between…
Sponsor: Indiana University • Aim: Diagnosis
Last updated Aug 16, 2026 00:00 UTC
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Smart contact lens could revolutionize glaucoma monitoring
Diagnosis CompletedThis study tested a new smart contact lens called miLens that records eye pressure patterns over 24 hours in 86 adults with glaucoma and healthy volunteers. Participants wore the lens in one eye and took smartphone readings every 15 minutes while awake. Researchers compared the l…
Sponsor: Smartlens, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 12:01 UTC
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Can a bangkok community eye check reveal hidden glaucoma risks?
Knowledge-focused CompletedThis study aims to measure how common glaucoma is among people aged 50 and older in the Bangkoknoi district of Bangkok, Thailand. Researchers will examine about 1,470 volunteers using standard eye tests and advanced imaging to detect signs of glaucoma and gather normal eye measur…
Sponsor: Siriraj Hospital • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Eye flakes and wrist pain: surprising connection found?
Knowledge-focused CompletedThis study examined whether pseudoexfoliation syndrome (an eye condition) is related to carpal tunnel syndrome (a wrist nerve problem). Researchers measured blood markers in 159 adults aged 50-80. The goal was to see if these conditions share a common cause, not to test a treatme…
Sponsor: Ankara Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Kids' glaucoma exams: standard anesthesia may improve accuracy
Knowledge-focused CompletedThis study looked at 120 children with glaucoma or suspected glaucoma who needed eye exams under anesthesia. The goal was to see if a standard anesthesia plan could produce consistent and reliable eye pressure measurements. Researchers measured how deep the anesthesia was and com…
Sponsor: Johannes Gutenberg University Mainz • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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App aims to clear up glaucoma drop confusion
Knowledge-focused CompletedThis study tested whether a simple app, available in English, Spanish, and Cantonese, could help glaucoma patients better remember their multiple eye drop schedules. Twenty participants either used the app or received standard instructions. After one month, researchers compared h…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Early glaucoma detection in babies could save sight, study hints
Knowledge-focused CompletedThis study followed 250 children under 4 years old with congenital glaucoma in France. Researchers wanted to see if finding the disease earlier leads to better eyesight at age 4. They measured vision and eye pressure to understand how timing of diagnosis affects long-term outcome…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC