Hereditary glaucoma
MONDO:0018174Hereditary glaucoma is a clinically diverse group of rare eye disorders with genetic predisposition characterized by elevated intraocular pressure (IOP) and glaucomatous changes of the optic nerve head, leading to field defects, visual loss and blindness. Hereditary glaucoma can be sub-classified as primary (congenital glaucoma, juvenile glaucoma) or secondary according to the presence or absence of systemic or other ocular anomalies (iridogoniodysgenesis, Stickler syndrome, Coats syndrome). The clinical presentation is variable and is based on age, severity of glaucoma, presence of ocular abnormalities and development of secondary IOP related abnormalities.
Also known as: hereditary glaucoma (disease), glaucoma, hereditary
55 clinical trials for this condition and its sub-types, 0 tagged with Hereditary glaucoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hereditary glaucoma
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Exfoliation syndrome 32 trials
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Juvenile open angle glaucoma 7 trials · 15 incl. sub-types
6 sub-types
- Glaucoma 1, open angle, l 8 trials
- Glaucoma 1, open angle, A 0 trials
- Glaucoma 1, open angle, J 0 trials
- Glaucoma 1, open angle, K 0 trials
- Glaucoma 1, open angle, M 0 trials
- Glaucoma 1, open angle, N 0 trials
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Congenital glaucoma 6 trials · 7 incl. sub-types
4 sub-types
- Primary congenital glaucoma 2 trials · 4 incl. sub-types Sub-types →
- Glaucoma 3, primary congenital, E 0 trials
- Glaucoma 3, primary infantile, B 0 trials
- Glaucoma type 1C 0 trials
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Anterior segment dysgenesis 3 1 trial
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Iris hypoplasia with glaucoma 1 trial
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OPTN-related open angle glaucoma 0 trials
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TEK-related primary glaucoma 0 trials
1 sub-type
- Glaucoma 3, primary congenital, E 0 trials
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Glaucoma 1, open angle, O 0 trials
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Glaucoma 1, open angle, P 0 trials
Most studied deeper sub-types
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Glaucoma Drug-Eluting contact lens trial halted after single patient
Disease control Stopped earlyThis study tested a special contact lens that slowly releases the glaucoma drug latanoprost, aiming to replace daily eye drops. Only one person enrolled before the study was stopped early. The goal was to check safety and whether the lens could lower eye pressure, but no conclusi…
Phase 1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Can your phone spot eye cancer? app tested for retinoblastoma
Diagnosis Stopped earlyThis study tested a smartphone app called CRADLE that uses a photo to detect leukocoria (a white glow in the pupil), which can be a sign of retinoblastoma, cataracts, or glaucoma. Researchers planned to compare the app's accuracy to a standard eye exam in children with these cond…
Sponsor: St. Jude Children's Research Hospital • Aim: Diagnosis
Last updated Sep 17, 2026 00:00 UTC
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Tiny study on eye pressure fluctuation in glaucoma patients ends early
Knowledge-focused Stopped earlyThis study aimed to measure how eye volume changes (a sign of pressure fluctuation) before and after cataract surgery in patients with exfoliative glaucoma, a type of glaucoma common in Brittany. Only 6 adults were enrolled before the study was terminated. The goal was to see if …
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC