Exfoliation syndrome

This study compares two devices used during cataract surgery to treat open-angle glaucoma. About 194 adults with mild to moderate glaucoma and cataracts will receive either the ELIOS device or a competitor device. The main goal is to see which one lowers eye pressure more effecti…

This study compares two FDA-approved laser treatments for open-angle glaucoma: the standard SLT and a newer, non-contact version called DSLT. Both aim to lower eye pressure and prevent vision loss. About 172 adults with glaucoma or high eye pressure will be randomly assigned to o…

This study compares two small implants (XEN-63 and PRESERFLO) placed during a quick surgery to lower eye pressure in adults with open-angle glaucoma. About 166 participants will be randomly assigned to one implant and followed for 2 years. The goal is to see if PRESERFLO works as…

This study compares three types of glaucoma surgery (Hydrus Microstent, incisional goniotomy, and excisional goniotomy) done at the same time as cataract surgery. About 243 adults with mild to moderate open-angle glaucoma will take part. The goal is to see which surgery lowers ey…

This study is testing a special laser called ELIOS to treat glaucoma at the same time as cataract surgery. The laser creates tiny channels in the eye to help fluid drain and lower eye pressure. About 46 adults with both cataracts and open-angle glaucoma will take part. The goal i…

This study tests whether a tiny drainage device called the Preserflo MicroShunt can lower eye pressure as well as the standard trabeculectomy surgery in adults with open-angle glaucoma. One hundred participants will be randomly assigned to receive one of the two procedures and wi…

This study tests whether a weak electrical current applied to the eye's surface can improve vision in people with open-angle glaucoma. Fifty adults with worsening vision loss will receive either real or sham stimulation over several sessions. The goal is to see if this safe, non-…

This study tests a device called the Tran cannula, used during cataract surgery to clean away debris from the eye's drainage system in patients with pseudoexfoliative glaucoma. The goal is to see if it lowers eye pressure better than standard irrigation. Fifty-eight adults with b…

This study tests whether a daily supplement called BrudyGlauco (containing DHA and citicoline) can help protect eyesight in people with glaucoma. About 108 participants will take either the supplement or a placebo for 12 months. The goal is to see if it slows vision loss and impr…

This trial tests a tiny device called the VisiPlate shunt to help drain fluid and lower eye pressure in people with open-angle glaucoma that hasn't responded to other treatments. About 165 adults will receive the implant and be followed to see if their eye pressure drops by at le…

This study tests a device called the Calibreye System, a small implant placed in the eye to help drain fluid and lower pressure in people with open-angle glaucoma. Researchers will check if it is safe and works well over 12 months in 60 adults. The goal is to see if the device ca…

This study tests if two devices placed in the eye can safely lower eye pressure in people with moderate to severe open-angle glaucoma. Participants have not responded well to drops or laser and are considering surgery. The goal is to see if these implants can be a less invasive a…

This study looks at whether a laser treatment called DSLT can reduce the natural ups and downs of eye pressure throughout the day in people with glaucoma. Researchers will measure eye pressure at three times during one day before the laser and again six months after. The goal is …

Researchers at a German university eye hospital collect and anonymize data from about 10,000 people with glaucoma, ocular hypertension, or suspected glaucoma. They study how often patients should return for check-ups and which treatments best lower eye pressure for each person. T…

This study looks at how well a minimally invasive glaucoma surgery called ab-interno trabeculotomy (AIT) holds up over the long term. Researchers will review the medical records of 200 glaucoma patients who had the surgery between 2019 and 2021 and invite them for a single follow…

This study looks at whether the stiffness of the cornea influences how much astigmatism (blurring from an irregularly shaped cornea) develops after cataract surgery in people with pseudoexfoliation syndrome, a condition that weakens eye tissues. Researchers will measure corneal b…

This study follows 132 adults having glaucoma surgery to see how their quality of life changes over six months. Patients fill out a questionnaire about vision-related daily activities before and after surgery. The goal is to compare different surgical techniques from the patient'…