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Eye flakes and wrist pain: surprising connection found?

NCT ID NCT06946030

Knowledge-focused Sponsor: Ankara Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examined whether pseudoexfoliation syndrome (an eye condition) is related to carpal tunnel syndrome (a wrist nerve problem). Researchers measured blood markers in 159 adults aged 50-80. The goal was to see if these conditions share a common cause, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand if pseudoexfoliation syndrome is linked to carpal tunnel syndrome, possibly leading to earlier detection.
What could go wrong
This is a small, completed observational study, not a treatment trial. Results may not apply to broader populations or lead to direct medical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

159 people

The number who actually took part.

Started

May 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Case group participants will be selected from patients diagnosed with PES during eye examination. After informed consent, EMG will be performed to evaluate for CTS. Boston CTS Questionnaire will assess symptom severity in CTS-positive patients. Demographics, comorbidities, EMG and questionnaire results will be recorded. Control group will consist of age/gender-matched patients with mechanical back, knee, or hip pain without CTS symptoms. They will also undergo EMG after consent. All demographic data, comorbidities, and EMG results will be documented for both groups.

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being between the ages of 50-80 * Having been diagnosed with PES during routine eye examination Exclusion Criteria: * History of major hand-wrist trauma or surgical intervention * Acromegaly * Presence of any structural abnormality in bone structure * Pregnancy * Gout * Rheumatoid arthritis * Connective tissue disease * Acromegaly * Thoracic outlet syndrome * Brachial plexopathy * Cervical disc herniation * Presence of cardiac pacemaker * Steroid users * Repetitive hand operations

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome exfoliation syndrome exfoliation syndrome, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS) Pseudoexfoliation syndrome

Contacts and locations

Locations

  • Department of Physical Therapy and Rehabilitation, University of Health Sciences, Ankara Training and Research Hospital

    Ankara, Altindag, 06230, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.