Hashimoto thyroiditis
MONDO:0007699An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism.
Also known as: lymphocytic thyroiditis, Hashimoto disease, Hashimoto hypothyroidism, Hashimoto thyroiditis, Hashimoto's disease, Hashimoto's syndrome, Hashimoto's thyroiditis, chronic lymphocytic thyroiditis
50 clinical trials for this condition and its sub-types, 15 tagged with Hashimoto thyroiditis itself.
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New booster aims to shield the vulnerable from COVID-19
Vaccine CompletedThis study tested an extra dose of the HIPRA COVID-19 vaccine in 241 adults with conditions like HIV, kidney disease, or autoimmune disorders that weaken the immune system. The goal was to see if the booster raises antibody levels against virus variants and remains safe. Research…
Phase 2/3 • Sponsor: Hipra Scientific, S.L.U • Aim: Vaccine
Last updated Jun 26, 2026 18:38 UTC
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Can a pill tame thyroid eye disease?
Disease control CompletedThis trial tests whether an oral medication called linsitinib can help people with active, moderate to severe thyroid eye disease, a condition that causes eye bulging and inflammation. Participants take either linsitinib or a placebo twice daily for 24 weeks. The main goal is to …
Phase 2/3 • Sponsor: Sling Therapeutics, Inc. • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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New drug VIS171 tested in humans for first time – could it tame autoimmune disease?
Disease control CompletedThis early-phase trial tested a new drug called VIS171 in 61 people: first in healthy volunteers, then in patients with autoimmune diseases. The main goal was to check safety and how the body processes the drug. No results on whether it actually helps the disease are available ye…
Phase 1 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Blood filter shows promise for autoimmune patients
Disease control CompletedThis study looked at a device called GLOBAFFIN that filters antibodies from the blood to help people with autoimmune diseases. It involved 34 adults and measured how much harmful antibodies were removed and if patients felt better. The goal was to see if the device is safe and wo…
Sponsor: Fresenius Medical Care Deutschland GmbH • Aim: Disease control
Last updated Jun 26, 2026 14:18 UTC
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Cutting salt and sugar may tame steroid side effects
Symptom relief CompletedThis study looked at whether a diet low in salt and sugar can reduce common side effects of corticosteroid treatment, such as weight gain, high blood pressure, and diabetes. Fifty adults with autoimmune diseases or asthma who were starting high-dose corticosteroids were randomly …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Scientists hunt for genetic and environmental triggers of rare muscle diseases
Knowledge-focused CompletedThis study looked at 719 people, including patients with autoimmune connective tissue diseases like myositis, their blood relatives, and healthy volunteers. Researchers collected blood samples and medical histories to find genetic and environmental factors that may trigger these …
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Hidden thyroid cancers: how common are they in patients with thyroiditis?
Knowledge-focused CompletedThis completed study from Minia University looked at 200 patients with autoimmune thyroiditis (an inflamed thyroid) who had thyroid surgery. The goal was to see how often thyroid cancer is found by accident when examining the removed tissue. Researchers checked for cancer in pati…
Sponsor: Minia University • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Massive study reveals COVID-19 risks for autoimmune patients
Knowledge-focused CompletedThis study looked at over 13,000 people with chronic inflammatory rheumatism or autoimmune diseases who had or were suspected to have COVID-19. Researchers tracked how many developed severe COVID-19 requiring intensive care or leading to death. They also examined risk factors lik…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Hashimoto's study probes hidden inflammation and reverse T3 levels
Knowledge-focused CompletedThis completed study from Ankara City Hospital Bilkent examined 179 people with Hashimoto's thyroiditis, an autoimmune condition that affects the thyroid. Researchers compared levels of reverse T3, a little-studied thyroid hormone, and inflammation markers in patients who were or…
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Rituximab infection risk under the microscope
Knowledge-focused CompletedThis completed study followed 73 people with autoimmune diseases like rheumatoid arthritis or multiple sclerosis who were starting treatment with rituximab. The goal was to track how many developed serious infections and to understand what factors increase that risk. Researchers …
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Scientists test designer immune molecules in autoimmune diseases
Knowledge-focused CompletedThis study looked at whether specially engineered versions of a natural immune protein (IL-2) can selectively boost regulatory T cells, which help calm the immune system. Researchers took blood samples from 67 people with various autoimmune or inflammatory conditions and tested t…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New drug LAD191 tested for safety in autoimmune patients
Knowledge-focused CompletedThis early-phase study tested the safety and tolerability of a new drug called LAD191 in 69 healthy adults and people with an autoimmune disease. Researchers gave single or multiple doses to see how the body processes the drug and if it causes side effects. The goal was to gather…
Phase 1 • Sponsor: Almirall, S.A. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC