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Diabetic polyneuropathy
MONDO:0001583Also known as: polyneuropathy in diabetes
55 clinical trials for this condition and its sub-types, 50 tagged with Diabetic polyneuropathy itself.
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Lotus seed supplement shows promise for diabetic nerve pain
Disease control CompletedThis completed study tested whether lotus seed capsules could improve nerve health, blood sugar, and immune function in 60 people with type 2 diabetes and nerve damage. Participants took either lotus seed or placebo capsules for 9 months alongside their regular diabetes treatment…
Sponsor: Riphah International University • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Lifestyle overhaul may ease diabetic nerve pain
Disease control CompletedThis study looked at whether a 12-week intensive lifestyle program focused on weight loss and diabetes control could improve diabetic peripheral neuropathy, a common nerve complication. Fifty adults with diabetes and a BMI between 30 and 45 took part. The program included diet, e…
Sponsor: Joslin Diabetes Center • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Could a simple exam catch diabetic nerve damage early?
Diagnosis CompletedThis study tested two simple bedside tools—the Neuropathy Disability Score and Neuropathy Symptom Score—to screen for diabetic nerve damage. Researchers compared them to standard nerve tests in 228 adults with diabetes. The goal was to see if these easy-to-use tools could help de…
Sponsor: Chulalongkorn University • Aim: Diagnosis
Last updated Jun 27, 2026 12:24 UTC
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Laser test could objectively measure nerve pain for first time
Diagnosis CompletedThis study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…
Sponsor: University of Utah • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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Electric pulses may bring back lost foot sensation in diabetes
Symptom relief CompletedDiabetic polyneuropathy damages nerves in the feet, dulling the sense of touch and raising the risk of unnoticed injuries. This trial tests whether transcutaneous electrical nerve stimulation (TENS) can restore that sensation. Researchers compare high-frequency TENS, low-frequenc…
Sponsor: Burdur Mehmet Akif Ersoy University • Aim: Symptom relief
Last updated Sep 21, 2026 13:00 UTC
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Sleep lessons may soothe diabetic nerve pain in small trial
Symptom relief CompletedThis study tested whether teaching good sleep habits could help people with painful diabetic nerve damage sleep better and feel better overall. Twenty-four patients were split into two groups: one received a booklet and face-to-face sleep training from a nurse, while the other co…
Sponsor: Trakya University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Light or nerve zap: which eases diabetic nerve pain better?
Symptom relief CompletedThis study tested two non-invasive treatments—low-level laser and transcutaneous vagus nerve stimulation—in 30 adults with diabetic neuropathy. The goal was to see which better improves blood flow and reduces nerve pain. Participants had diabetes for over 5 years and stable blood…
Sponsor: Horus University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Electric baths may ease diabetic nerve pain and improve balance
Symptom relief CompletedThis study tested whether adding a four-cell galvanic bath therapy to standard rehabilitation could reduce pain and improve balance in people with diabetic nerve damage. 66 adults with type 2 diabetes and diabetic neuropathy participated. Over 4 weeks, some received the bath ther…
Sponsor: Ankara Etlik City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Light and sound waves ease diabetic nerve pain in new study
Symptom relief CompletedThis study tested a combined laser and ultrasound treatment for people with type 2 diabetes who have early nerve damage in their feet. Sixty participants received either the real treatment or a placebo over 24 sessions. The results showed that the treatment helped reduce pain, bu…
Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Could a spice compound ease diabetic nerve pain?
Symptom relief CompletedThis study tested whether adding thymoquinone, a compound from black seed oil, to the standard pain drug pregabalin could better relieve nerve pain in people with diabetes. Fifty adults with diabetic peripheral neuropathy took both treatments daily for two months. Researchers mea…
Phase 4 • Sponsor: Hawler Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Laser or exercise: which eases diabetic nerve pain better?
Symptom relief CompletedThis study looked at two ways to help people with diabetic nerve pain in their legs: high-intensity laser therapy and moderate aerobic exercise. Sixty adults with symptoms like numbness, tingling, or burning took part. The goal was to see which approach improves leg function and …
Sponsor: Deraya University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Can ultrasound spot early joint wear in diabetic nerve damage?
Knowledge-focused CompletedResearchers are using ultrasound to measure the thickness of ankle cartilage in people with type 2 diabetes who have nerve damage, and comparing it with healthy adults. Diabetic polyneuropathy may change how the lower limbs move, which could affect the ankle joint. The study incl…
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Blood marker may reveal hidden fall danger in diabetes patients
Knowledge-focused CompletedThis study looks at whether a substance in the blood called neurofilament light chain (NfL) is linked to how severe nerve damage is, how well people balance, and their risk of falling. Researchers will measure NfL levels in 80 adults with type 2 diabetes, some with and some witho…
Sponsor: Kanuni Sultan Suleyman Training and Research Hospital • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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New study uses ultrasound to uncover hidden nerve changes in diabetic patients with carpal tunnel
Knowledge-focused CompletedThis completed observational study looked at 84 people to understand how diabetic polyneuropathy (nerve damage from diabetes) changes the median nerve in patients with carpal tunnel syndrome. Researchers used advanced ultrasound techniques, including shear wave elastography and m…
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC