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Lotus seed supplement shows promise for diabetic nerve pain

NCT ID NCT06778018

Disease control Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study tested whether lotus seed capsules could improve nerve health, blood sugar, and immune function in 60 people with type 2 diabetes and nerve damage. Participants took either lotus seed or placebo capsules for 9 months alongside their regular diabetes treatment. Researchers measured changes in body mass index, blood sugar, cholesterol, liver and kidney function, nerve damage scores, and immune markers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lotus seed (Nelumbo nucifera) capsules
What this could lead to
If it works, this could point toward a natural supplement to help manage diabetic nerve damage and improve blood sugar control.
What could go wrong
This is a small, completed trial with only 60 participants, so results may not apply to everyone. Dietary supplements can have variable effects and are not a substitute for standard diabetes care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Dec 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants who have been clinically diagnosed with T2DM (Type 2 Diabetes Mellitus). * Participants who have been clinically diagnosed with neuropathy symptoms for at least 1 year. * Both male and female participants. * Participants aged 40 years and older. * Participants capable of understanding basic instructions, either independently or with assistance from their family. Exclusion Criteria: * Individuals with a clinical diagnosis of cardiovascular conditions. * Cancer patients will be excluded from the study. * Individuals diagnosed with rheumatoid arthritis. * Individuals with a urinary tract infection. * Individuals diagnosed with psychological disorders. * Pregnant or breastfeeding women.

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Conditions

The condition(s) this trial relates to.

diabetic kidney disease diabetic polyneuropathy type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetes mellitus type 2 Diabetic nephropathies

Contacts and locations

Locations

  • Riphah international university

    Lahore, Punjab Province, 54000, Pakistan

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