Coronary stenosis

This trial compares two types of patches used to close the artery after carotid endarterectomy, a surgery that removes blockages in the neck artery to prevent stroke. The Accuseal patch, a newer synthetic option, is tested against the Bovine Pericardial patch, which has been used…

This trial compares two types of drug-eluting stents—tiny mesh tubes that prop open arteries—in people with completely blocked coronary arteries. One stent uses a coating that dissolves over time (bioresorbable polymer) to release the drug sirolimus, while the other has a permane…

This study tested whether using ultrasound inside the heart arteries (IVUS) to guide stent placement works better than standard X-ray guidance for people with a blockage in the left main coronary artery. About 800 patients were randomly assigned to one of the two methods and foll…

This study looked at 1,500 people with severe blockages in three heart arteries. It compared a less invasive procedure using a pressure wire to guide stent placement (FFR-guided PCI) with open-heart bypass surgery (CABG). The goal was to see if the stent approach could match the …

This study tested a new balloon catheter called SINOMED CBC for treating narrowed coronary arteries. It involved 136 patients with stable or unstable angina or evidence of heart muscle ischemia. The device was compared to a standard balloon catheter to see if it was as safe and e…

This study looked at how well the Xience Sierra drug-coated stent works in a broad group of heart disease patients, including those with diabetes or prediabetes. Over 1,700 participants received the stent during a routine procedure to open blocked arteries. Researchers tracked he…

This study tested a special balloon coated with medication to reopen completely blocked heart arteries in 309 people. The balloon delivers drug to keep the artery open without leaving a permanent stent. Researchers checked if the artery stayed open and if there were any heart pro…

This study tested a virtual cardiac rehabilitation program using a smartphone app, a fitness wristband, and a blood pressure monitor for people who recently had a heart attack, heart surgery, or a stent. The goal was to see if this home-based program could improve walking ability…

This study looked at whether using a heart ultrasound probe (TEE) during low-risk coronary artery bypass surgery should be done routinely or only when needed. Researchers enrolled 40 patients and checked if it was possible to randomly assign them to one of two groups. The goal is…

This study looked at data from 100 patients who had heart artery imaging and pressure measurements. Researchers developed a new computer algorithm to analyze ultrasound images of the arteries and estimate how much they block blood flow. The goal was to see if the algorithm could …

This study looked at 90 people with low or medium heart risk to see if tiny, non-blocking plaques in the heart arteries affect how blood clots and how blood vessels work. Participants had a special CT scan to find these small plaques, and their blood was tested for clotting activ…

This study involved 150 people with completely blocked heart arteries who had a special procedure called STAR. Researchers wanted to find the best time to place a stent afterward—either 5-7 weeks or 12-14 weeks later. The goal was to see which timing leads to a more successful st…