Chronic ulcer of skin

This study tests whether sap from the Pterocarpus indicus tree can help heal small skin ulcers (sores) in remote areas of Papua New Guinea. 222 people with sores smaller than a dime will get either the plant sap, Savlon antiseptic cream, or no treatment. Researchers will check he…

This study tests whether a repairing gel (Supraz) combined with a platelet-rich plasma-fibrin glue can eliminate odor and help heal chronic wounds that haven't improved with standard care. About 40 adults with a single wound lasting at least 3 months will receive either the new t…

This program offers selexipag (Uptravi) to a single patient with Buerger's disease who has a wound that won't heal. The goal is to see if the drug can help control the disease and improve wound healing. This is not a cure, and the patient may need ongoing treatment.

This phase 3 trial tests a donor stem cell treatment called Allo-APZ2-CVU for people with chronic venous leg ulcers that haven't healed with standard therapy. About 250 adults with ulcers between 1 and 25 cm² will receive either the cell therapy or a placebo applied directly to t…

This study tests whether a special lipid cream (EpiCeram) can prevent healed chronic wounds—like diabetic foot ulcers or pressure sores—from reopening. About 100 adults with recently healed wounds will apply either the cream or Vaseline for 3 months. Researchers will measure skin…

This small study is testing Corplex P, a device made from donated human umbilical cord tissue, to see if it helps heal wounds that won't close on their own, like diabetic foot ulcers. Ten people will receive the device as part of their standard wound care. Researchers will track …

This study tests whether injecting platelet-rich plasma (PRP) directly into grade III ulcers can speed up healing. PRP is made from a small amount of the patient's own blood, processed to concentrate healing factors. Fifty adults with ulcers older than two weeks will receive eith…

This observational registry will follow 5,000 adults with various wounds—like diabetic foot ulcers, burns, or surgical wounds—to see how different treatments (e.g., hydrocolloid, foam, silver dressings) perform in everyday medical settings. Researchers will measure wound healing,…

This study looks at how low-level laser therapy (red light at 660 nm) affects the stiffness of chronic and burn wounds. Researchers will measure stiffness before and after a 3-minute laser treatment using two devices: OCT and MyotonPRO. The goal is to see if laser therapy changes…