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Could tree sap heal skin sores? new trial in PNG tests ancient remedy

NCT ID NCT07264686

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study tests whether sap from the Pterocarpus indicus tree can help heal small skin ulcers (sores) in remote areas of Papua New Guinea. 222 people with sores smaller than a dime will get either the plant sap, Savlon antiseptic cream, or no treatment. Researchers will check healing after 7 and 14 days.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pterocarpus indicus plant sap
What this could lead to
If it works, this could provide a cheap, accessible treatment for skin sores in remote areas where medicines are hard to get.
What could go wrong
This is a small Phase 2 trial testing a plant sap against a standard cream and no treatment. The results may not apply to larger or more severe ulcers, and the plant sap's effectiveness is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 222 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria: * Infected skin ulcer suspected with one or more predominantly moist ulcerative skin lesions of less than 1 cm diameter in greatest dimension and larger than 0.5cm in largest dimension with a predominantly moist surface, occurring below the knee. * Accepted and signed informed consent by a legal guardian (relative or teacher) * Ability and willingness to comply with the requirements of the study protocol including follow up visits. Exclusion Criteria: * Children younger than 5 years old. * Ulcer presenting with a crust (not predominantly moist surface), or dimensions different to those specified in point 1 above. * Refusal at ward level or village chief (for village inclusion), or refusal of individual or guardian (for individual inclusion). * Answered yes when asked if had taken antibiotics in the last week or presents with visible signs of ulcer treatment e.g. wound dressing.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vunapope Hospital, and surrounding area

    Kokopo, EAST NEW Britan, Papua New Guinea

More trials for these conditions

Other studies related to the condition(s) this trial covers.