Aphasia
MONDO:0000598A language disorder that involves an acquired impairment of any language modality such as producing or comprehending spoken or written language.
108 clinical trials for this condition and its sub-types, 95 tagged with Aphasia itself.
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Sub-types of Aphasia
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Nominal aphasia 18 trials
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Brain implant may turn thoughts into speech for people with aphasia
Disease control Not yet recruitingThis study tests a brain-computer interface called BrainGate2 in people with expressive aphasia, a condition where stroke damage makes it hard to speak. Researchers place small sensors in the brain areas that control speech, then record brain activity while participants try to sp…
Sponsor: Leigh R. Hochberg, MD, PhD. • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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Can a computer game help stroke survivors find their words again?
Disease control Not yet recruitingThis study tests a computer-based practice method to help people with aphasia—a language disorder often caused by stroke—retrieve words more easily. Participants practice naming pictures with or without cues and receive feedback, repeating items until they meet a learning goal. T…
Sponsor: Albert Einstein Healthcare Network • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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New brain test aims to unravel language confusion in dementia
Diagnosis Not yet recruitingThis study is testing a new cognitive assessment called the ExéSem battery, designed to help doctors tell the difference between language problems caused by memory loss versus those caused by thinking difficulties. Researchers will enroll 140 people, including those with Alzheime…
Sponsor: Hospices Civils de Lyon • Aim: Diagnosis
Last updated Jun 27, 2026 12:30 UTC
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Can an AI app give a voice to brain tumor patients?
Symptom relief Not yet recruitingThis trial tests whether a smartphone app called LISTEN can help people with brain tumors who have trouble speaking (aphasia) communicate more easily. The app uses artificial intelligence to adapt to each user's needs and can be used with voice input and output. Researchers will …
Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jul 30, 2026 00:00 UTC
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Acupuncture with electric current may help stroke survivors speak again
Symptom relief Not yet recruitingThis study tests whether adding electroacupuncture at specific acupoints (Xuanzhong and Tongli) to standard speech therapy improves language recovery in people with post-stroke aphasia. Participants receive daily electroacupuncture sessions for four weeks, plus speech therapy. Th…
Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Could a gentle brain ZAP boost speech recovery after stroke?
Symptom relief Not yet recruitingThis study explores whether a non-invasive brain stimulation technique called tDCS can be practically used during routine speech therapy for people who have had a stroke and now have aphasia (trouble speaking or understanding language). Researchers will enroll 30 stroke survivors…
Sponsor: Casa Colina Hospital and Centers for Healthcare • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Could 100 hours of speech therapy transform life after stroke?
Symptom relief Not yet recruitingThis trial tests whether an intensive, personalized speech therapy program (ICAP) helps people with post-stroke aphasia communicate better and feel better. 334 adults who had a stroke at least 3 months ago will be randomly assigned to either ICAP (100 hours over 4 weeks) or stand…
Sponsor: University College, London • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Brain zaps show promise for stroke speech loss
Symptom relief Not yet recruitingThis study tests whether a mild electrical current applied to the scalp (tDCS) can improve naming ability in people who have trouble speaking after a recent stroke. Twenty-eight adults with aphasia will receive either real or sham stimulation over five days. The goal is to see if…
Phase 3 • Sponsor: Dr. Ram Manohar Lohia Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Can ancient chinese music therapy help stroke survivors speak again?
Symptom relief Not yet recruitingThis study tests whether a special type of speech training using five musical tones can help people with aphasia (trouble speaking) after a stroke. Researchers will enroll 120 adults who had a stroke and have non-fluent aphasia. Participants will receive either five-tone therapy …
Sponsor: Fujian University of Traditional Chinese Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Could a light beam reboot Stroke-Damaged brains?
Symptom relief Not yet recruitingThis study tests a special light therapy (850 nm) on 66 adults who had a stroke within the past year and now have trouble speaking or understanding language (aphasia). The goal is to see if shining this light on the head can improve brain activity and language skills. Participant…
Sponsor: Pusan National University Yangsan Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Music may boost attention and language in stroke survivors
Symptom relief Not yet recruitingThis study tests whether listening to music for 30 minutes a day for 8 weeks can improve attention, language, and quality of life in people with aphasia after a stroke. Researchers will compare music listening to audiobook listening and a control group. The trial involves 45 adul…
Sponsor: Purdue University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Can brain scans reveal hidden language struggles after stroke?
Knowledge-focused Not yet recruitingThis study looks at stroke survivors who have mild aphasia—a condition causing language difficulties. Researchers want to see if these individuals also struggle with 'executive control' of language, which helps us manage and switch between words and ideas. By testing 30 participa…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC