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Can ancient chinese music therapy help stroke survivors speak again?

NCT ID NCT07329751

Symptom relief Sponsor: Fujian University of Traditional Chinese Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special type of speech training using five musical tones can help people with aphasia (trouble speaking) after a stroke. Researchers will enroll 120 adults who had a stroke and have non-fluent aphasia. Participants will receive either five-tone therapy or standard melodic intonation training for four weeks. The goal is to see if the five-tone approach improves language fluency and communication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Five-tone speech training (melodic intonation therapy based on Traditional Chinese Medicine)
What this could lead to
If it works, this could offer a new, non-drug therapy to help people with aphasia speak more fluently after a stroke.
What could go wrong
This is an early-stage study with no phase, so results are uncertain. The therapy may not improve language more than standard training, and benefits may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Eligibility Criteria Inclusion Criteria: Age between 18 and 70 years Right-handed Native Chinese speakers Clinical diagnosis of post-stroke aphasia caused by ischemic stroke, confirmed by CT or MRI Diagnosis of non-fluent aphasia based on the Western Aphasia Battery (WAB), with BDAE severity rating of 1-5 Time since stroke onset ≥ 2 weeks Stable vital signs, clear consciousness, and no severe cognitive impairment Ability to understand the study procedures and provide written informed consent (or consent provided by a legally authorized representative) Exclusion Criteria: History of aphasia or neurological disease not caused by stroke (e.g., traumatic brain injury, brain tumor, neurodegenerative diseases) Severe visual or auditory impairments that would interfere with task performance Severe cognitive impairment or disorders of consciousness preventing cooperation with language assessment or intervention Severe dysarthria or apraxia of speech that precludes valid language assessment History of epilepsy or other severe neurological conditions Severe systemic diseases (e.g., severe cardiopulmonary dysfunction, renal failure, hepatic failure, malignancy) Psychiatric disorders (e.g., schizophrenia, severe depression, or other major psychiatric illnesses) Contraindications to MRI or fNIRS assessment (e.g., metallic implants, severe claustrophobia)

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Conditions

The condition(s) this trial relates to.

aphasia progressive non-fluent aphasia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aphasia

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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