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Brain zaps show promise for stroke speech loss

NCT ID NCT07496645

Symptom relief Sponsor: Dr. Ram Manohar Lohia Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a mild electrical current applied to the scalp (tDCS) can improve naming ability in people who have trouble speaking after a recent stroke. Twenty-eight adults with aphasia will receive either real or sham stimulation over five days. The goal is to see if the treatment helps them name pictures more accurately and quickly.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could point toward a simple, non-invasive way to improve language recovery soon after a stroke.
What could go wrong
This is a small, early-phase trial with only 28 people, so results may not apply widely. Previous studies have been mixed, and any improvements may be short-lived.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 28 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aphasic patients with left middle cerebral artery territory Acute Ischemic Stroke * Patients between 18-65 years of age. * Within 5 days of onset of stroke. Exclusion Criteria: * Patients with malignant Middle Cerebral Artery territory infarcts and previous clinical history of cerebral hemisphere stroke. * Patients with history of previous brain surgery or skull defect due to surgery e.g. craniectomy. * Patients with epilepsy. * Patients with history of significant head trauma in the last 1 month. * Patients with documented history of major depression prior to stroke. * Patients with alcohol/drug abuse in the past 6 months. * Patients with prior significant cognitive impairment. * Pacemaker in situ, cochlear implant in situ. * Pregnancy.

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Conditions

The condition(s) this trial relates to.

aphasia brain ischemia cerebral infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute ischemic cerebrovascular disease Aphasia following cerebral infarction Aphasia, acquired Post-stroke aphasia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi

    New Delhi, National Capital Territory of Delhi, 110001, India

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