New speech therapy trial aims to help stroke survivors find their words
NCT ID NCT07036406
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of speech therapy for people with aphasia, a language disorder often caused by stroke. One therapy, called Semantic Feature Analysis (SFA), helps people name objects by describing their features. The other adds metacognitive strategy training (SFA+MST), which teaches people to think about how they find words. Researchers will enroll 40 adults with aphasia to see if the combined approach leads to better word-finding and more natural conversation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Semantic Feature Analysis (SFA) and SFA plus Metacognitive Strategy Training (MST)
- What this could lead to
- If successful, this could point toward a more effective speech therapy for people with aphasia, helping them find words and speak more easily in daily life.
- What could go wrong
- This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. The added metacognitive training may not provide extra benefit over standard therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 89 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have aphasia due to a single acute event (e.g., left-hemisphere stroke, traumatic brain injury) * Be at least six-months post aphasia-onset, * Be a proficient English speaker, * Have normal or corrected to normal hearing (i.e., hearing aids) and vision (i.e., eyeglasses), * Have no history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug/alcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems Exclusion Criteria: * A history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug/alcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems, * Children under the age of 18, * Adults over the age of 89, * Uncorrected hearing and vision.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Teachers College, Columbia University
RECRUITINGNew York, New York, 10027, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can hearing your own voice rewire speech after a stroke?
- Brain implant may turn thoughts into speech for people with aphasia
- Zapping the brain to restore speech after stroke?
- Can exercise boost reading recovery in stroke survivors?
- Can training the brain to think about words boost recovery from stroke-related aphasia?
- Can an AI app give a voice to brain tumor patients?