Herbal mix and cancer drug join forces to fight fluid in lungs

NCT ID NCT07670338

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether adding a Chinese herbal formula (Xuanyin Ning) to a standard cancer drug (bevacizumab) can better control malignant pleural effusion—fluid buildup in the chest caused by advanced lung cancer. About 308 participants will receive either the herbal formula or a placebo, along with bevacizumab injected into the chest after drainage. The goal is to see if the combination improves fluid control, breathing, and quality of life over 8 weeks of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Xuanyin Ning Formula (Chinese herbal granules) and bevacizumab (a cancer drug injected into the chest)

What this could lead to

If it works, this combination could offer a new way to better control fluid buildup in the chest, improving breathing and quality of life for people with advanced lung cancer.

What could go wrong

This is an early-stage trial with no phase listed, so results are uncertain. The herbal formula may not add benefit over standard care, and bevacizumab carries risks like bleeding or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myeloproliferative disorder, chronic, with eosinophilia non-small cell lung carcinoma Pleural Effusion, Malignant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Chest Hospital

    Shanghai, Shanghai Municipality, 200030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Tenth People's Hospital Chongming Branch

    Shanghai, Shanghai Municipality, 202157, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xinxiang Medical University

    Xinxiang, Henan, 453100, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Weifang Traditional Chinese Medicine Hospital 或 Weifang Traditional Chinese Hospital

    Weifang, Shandong, 261041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wuhan First Hospital

    Wuhan, Hebei, 430022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

    Shanghai, Shanghai Municipality, 200437, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••