Researchers test if electronic health records can mimic Gold-Standard cancer studies

NCT ID NCT07485166

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether information from electronic health records can be used to recreate the results of two earlier clinical trials (CheckMate 017 and 057) for advanced lung cancer. Researchers will compare survival outcomes in patients who started either nivolumab or docetaxel, using data from over 800 patients. The goal is not to find a new treatment, but to see if real-world data can reliably answer clinical questions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that real-world data can reliably replace some traditional trials, speeding up research and lowering costs.

What could go wrong

This is an observational study, not a new treatment test. Results may not match the original trials due to data quality or hidden biases.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma non-small cell squamous lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Somerville, Massachusetts, 02145, United States