Nasal spray could offer quick relief for Parkinson's 'Off' moments
NCT ID NCT07156773
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests a new nasal spray called XJN010 for people with Parkinson's disease who have 'off' episodes—times when their regular medication stops working and symptoms return. The trial will include 84 adults aged 30 to 85 and will measure how well the spray improves movement and how long it takes to switch from 'off' to 'on' state. The goal is to see if the spray is safe and effective for managing these difficult episodes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
XJN010 nasal spray
What this could lead to
If successful, this nasal spray could offer a fast-acting way to reduce the duration and severity of 'off' episodes, improving daily function for people with Parkinson's.
What could go wrong
This is an early Phase 2 trial with only 84 participants, so results may not apply to everyone. The spray may not work better than placebo, and side effects are still being studied.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The First Affiliated Hospital of Jinan University (Guangzhou Overseas Chinese Hospital)
RECRUITINGGuangzhou, Guangdong, 511434, China
Contact Phone: •••-•••-•••• Email: •••••@•••••