Xenon MRI breathes new life into lung disease detection

NCT ID NCT04991454

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explored whether a special type of MRI using inhaled xenon gas could detect changes in the small blood vessels of the lungs in people with pulmonary hypertension. The goal was to see if this imaging method could track disease progression or response to treatment. However, the trial was terminated early and only enrolled 12 participants, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyperpolarized xenon gas

What this could lead to

If successful, this could provide a new, non-invasive way to monitor lung blood vessel health in pulmonary hypertension patients.

What could go wrong

The trial was terminated early and enrolled only 12 people, so results are very limited. It is unclear if the technique will be reliable or useful in practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic thromboembolic pulmonary hypertension pulmonary arterial hypertension pulmonary hypertension pulmonary hypertension owing to lung disease and/or hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States