Phone therapy shows promise for weight loss in new study

NCT ID NCT04447313

Ongoing Disease control Sponsor: Fred Hutchinson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase III trial tests whether telephone-based Acceptance and Commitment Therapy (ACT) helps overweight or obese adults lose more weight than standard behavioral therapy. About 418 participants will receive coaching over the phone and use a Fitbit and scale to track progress. The study aims to see which approach leads to at least 10% weight loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Telephone-based coaching (Acceptance and Commitment Therapy or standard behavioral therapy)
What this could lead to: If successful, this could show that Acceptance and Commitment Therapy is more effective than standard behavioral therapy for helping people lose weight.
What could go wrong: This is a behavioral intervention, not a drug, so results may vary widely. Weight loss can be difficult to maintain, and the study's findings may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY-RELATED MALIGNANT NEOPLASM

Contacts and locations

Locations

Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, 98109, United States

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Other studies related to the condition(s) this trial covers.