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Can online exercise help young brain tumor survivors recover?

NCT ID NCT05367076

Symptom relief Sponsor: The Hospital for Sick Children Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 24, 2026 · Last updated Sep 25, 2026 · Updated 1 time

Summary

Researchers are testing whether a 12-week web-based aerobic exercise program can be delivered by community fitness instructors to children who have survived brain tumors. The study enrolls 26 participants aged 6 to 17 who are in remission and between 1 and 15 years past diagnosis. The program includes group sessions three times a week with games and sports, and the study measures how many children attend, complete assessments, and how instructors rate the platform.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a web-based aerobic exercise program delivered by community fitness instructors
What this could lead to
If it works, this could give families a home-based way to help children recover thinking skills and fitness after brain tumor treatment.
What could go wrong
This is a small feasibility study, so it cannot prove the exercise improves cognition. Many children may not complete the program, and the web platform may not work well for all instructors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

26 people

The number who actually took part.

Started

Oct 2021

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Between 6 years and 17 years and 11 months of age at time of enrollment 2. Diagnosed with a brain tumour 3. 1 to 15 years between diagnosis and time of study enrollment 4. Medically stable (i.e. must be in remission) as determined by a permanent SickKids staff Neuro-Oncologist 5. Either declare English as their native language or have at least two years of schooling in English at the time of their first assessment 6. Have a parent or legal guardian willing to complete the Health and Quality of Life measures 7. Informed consent (and assent, where applicable) will be obtained from the participants and/or their legal guardians Exclusion Criteria: 1. Any condition or diagnosis, that could in the opinion of the Principal Investigator or delegate, interfere with the participant's ability to comply with study instructions, might confound the interpretation of the study results, or put the participant at risk 2. Diagnosed with a neurodevelopmental or neurological disorder, cerebral palsy, developmental delay or learning disability prior to initial brain tumour diagnosis that would preclude safe participation 3. Receiving palliative care 4. Require sedation for neuroimaging 5. Have ferrous metal implants (i.e. cochlear implant, braces, etc.) 6. Have a programmable shunt 7. Pregnant 8. Completed any prior cognitive rehabilitation intervention within three months of enrollment

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment Pediatric brain tumor

Contacts and locations

Locations

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

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