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Dialysis and the brain: what MRI scans and memory tests reveal

NCT ID NCT04433455

Knowledge-focused Sponsor: Huashan Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 23, 2026 · Last updated Sep 24, 2026 · Updated 1 time

Summary

This observational study looks at what factors relate to cerebrovascular disease and cognitive function in adults receiving long-term hemodialysis. Researchers will use MRI scans to measure white matter hyperintensity severity and the Mini-Mental State Examination to assess thinking and memory. The study enrolls 20 maintenance hemodialysis patients aged 50 to 85 who have been on dialysis for more than three months. No treatment is given; the goal is to understand how brain blood vessel changes and cognition connect in this population.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers identify which factors track with brain blood vessel disease and mental decline in dialysis patients, that could guide future screening or prevention strategies for this group.
What could go wrong
This is a small observational study of 20 people, so it can only show associations, not cause and effect. Findings may not apply to dialysis patients outside the study's age range or health profile.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2020

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

maintenance hemodialysis patients

Ages

50 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. maintenance hemodialysis patients who are younger than 85 years old and older than 50 years old, regardless of gender 2. dialysis vintage is greater than 3 months; Exclusion Criteria: 1. Those with severe infection and anemia (Hb \<60g / L); 2. Those with severe mental illness, metabolic diseases and immune system diseases; 3. Patients with abnormal liver function

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Conditions

The condition(s) this trial relates to.

cerebrovascular disorder Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebrovascular disorders Cognitive impairment Hemodialysis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Huashan Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200040, China

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