Watermelon wonder: daily snack may improve gut health in overweight young adults

NCT ID NCT06588218

Recruiting now Disease control Sponsor: Florida State University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether eating 2.5 cups of fresh watermelon every day for six weeks can improve gut health, including increasing good bacteria, and boost heart health in young adults aged 18-30 who are overweight or have obesity. Participants will be randomly assigned to eat either watermelon or a low-fat control snack. Researchers will measure changes in gut and mouth bacteria, digestion speed, and blood vessel function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fresh watermelon
What this could lead to: If it works, this could show that a simple dietary change like eating watermelon can improve gut and heart health in young adults with overweight or obesity.
What could go wrong: This is a small, early-stage study with only 36 participants, so results may not apply to everyone. The effects may be small or no different from the control snack.

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Conditions

The condition(s) this trial relates to.

Dysbiosis Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DYSBIOSIS OBESITY AND OVERWEIGHT

Contacts and locations

Locations

Florida State University - Gut Biome Lab
RECRUITING

Tallahassee, Florida, 32306, United States

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