Warm dye may ease pain during key fertility exam

NCT ID NCT07226310

Recruiting now Symptom relief Sponsor: University of Oklahoma Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study tests whether warming the contrast dye used in a hysterosalpingogram (HSG) — a standard X-ray test for blocked fallopian tubes — can reduce pain and cramping during the procedure. About 240 women aged 18–45 will be randomly assigned to receive either warm or room-temperature dye. The goal is to see if warm dye leads to less discomfort and fewer false signs of blockage, which can happen when the tubes spasm from the cold liquid.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: warmed contrast dye
What this could lead to: If it works, this could make a common fertility test less painful and more accurate by reducing false blockages.
What could go wrong: This is a very early, small trial. Warming the dye may not meaningfully reduce pain or improve test results, and the effect may vary from person to person.

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Conditions

The condition(s) this trial relates to.

infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFERTILITY

Contacts and locations

Locations

University of Oklahoma Health Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

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