Can palm skin cells toughen amputation stumps?
NCT ID NCT03947450
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether injecting a person's own skin cells from the palm or sole into their amputation stump can thicken the skin and reduce breakdown. Researchers will enroll 50 adults with below-knee amputations who use a prosthetic. The goal is to see if this treatment is safe and helps prevent sores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
autologous skin fibroblasts (the patient's own skin cells from palm or sole)
What this could lead to
If it works, this could offer a way to strengthen stump skin, reducing sores and improving prosthetic use for amputees.
What could go wrong
This is a small Phase 2 trial with only 50 participants, so results may not apply broadly. The treatment involves injections and carries risks like infection or no improvement.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Dermatology at Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••