Can palm skin cells toughen amputation stumps?
NCT ID NCT03947450
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether injecting a person's own skin cells from the palm or sole into their amputation stump can thicken the skin and reduce breakdown. Researchers will enroll 50 adults with below-knee amputations who use a prosthetic. The goal is to see if this treatment is safe and helps prevent sores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- autologous skin fibroblasts (the patient's own skin cells from palm or sole)
- What this could lead to
- If it works, this could offer a way to strengthen stump skin, reducing sores and improving prosthetic use for amputees.
- What could go wrong
- This is a small Phase 2 trial with only 50 participants, so results may not apply broadly. The treatment involves injections and carries risks like infection or no improvement.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Dermatology at Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
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Other studies related to the condition(s) this trial covers.
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