Slower lung inflation may protect preterm Babies' lungs
NCT ID NCT07101419
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial studies whether a slower inflation setting (long pressure rise time) on mechanical ventilators can improve oxygen levels in extremely preterm infants compared to the standard faster setting. About 68 babies born before 28 weeks will be randomly assigned to both settings in a crossover design. The goal is to find a gentler way to support breathing and reduce lung damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mechanical ventilator setting (pressure rise time)
What this could lead to
If it works, this could lead to a gentler ventilator setting that reduces lung damage in extremely preterm babies.
What could go wrong
This is a small, early-stage crossover trial with only 68 infants, so results may not apply broadly. The intervention is a temporary setting change, not a cure or long-term treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Joan Kirner Women's and Children's Hospital
Saint Albans, Victoria, 3021, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mercy Hospital for Women
Heidelberg, Victoria, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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The Royal Women's Hospital
Parkville, Victoria, 3051, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••