Parkinson's drug trial halted early: what happened?
NCT ID NCT06822517
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested an experimental drug called VENT-02 in 29 people with mild to moderate Parkinson's disease. The drug aims to reduce brain inflammation by blocking a protein called NLRP3. The trial was terminated early, so we don't have clear results on whether it helps symptoms or slows the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
VENT-02 (an NLRP3 inhibitor)
What this could lead to
If successful, this could point toward a treatment that slows Parkinson's progression by targeting inflammation in the brain.
What could go wrong
This was a very early, small trial that was terminated, so results are limited. It is unclear if VENT-02 is safe or effective for Parkinson's.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Investigative Site
Fountain Valley, California, 92708, United States
-
Investigative Site
San Jose, California, 95124, United States
-
Investigative Site
West Hills, California, 91307, United States
-
Investigative Site
Englewood, Colorado, 80113, United States
-
Investigative Site
Aventura, Florida, 33180, United States
-
Investigative Site
Boca Raton, Florida, 33486, United States
-
Investigative Site
Coral Gables, Florida, 33134, United States
-
Investigative Site
Coral Springs, Florida, 33067, United States
-
Investigative Site
Cutler Bay, Florida, 33189, United States
-
Investigative Site
Daytona Beach, Florida, 32117, United States
-
Investigative Site
Doral, Florida, 33178, United States
-
Investigative Site
Jacksonville, Florida, 32256, United States
-
Investigative Site
Maitland, Florida, 32751, United States
-
Investigative Site
Miami, Florida, 33135, United States
-
Investigative Site
Miami, Florida, 33165, United States
-
Investigative Site
Winter Park, Florida, 32789, United States
-
Investigative Site
Scarborough, Maine, 04074, United States
-
Investigative Site
Farmington Hills, Michigan, 48334, United States
-
Investigative Site
Abington, Pennsylvania, 19001, United States
-
Investigative Site
Memphis, Tennessee, 38157, United States
-
Investigative Site
Cypress, Texas, 77429, United States
-
Investigative Site
Round Rock, Texas, 78681, United States
-
Investigative Site
Spokane, Washington, 99202, United States