Knee infection fight: new antibiotic injection method tested
NCT ID NCT07282782
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests three ways to give the antibiotic vancomycin during knee replacement surgery: into the joint, into the bone, or through a vein. The goal is to see if the simpler joint injection works as well as the others to prevent serious infections. Thirty adults having a first-time knee replacement will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vancomycin
What this could lead to
If successful, this could show that injecting vancomycin directly into the knee joint works as well as other methods, reducing extra wounds and costs.
What could go wrong
This is a small early-phase study with only 30 participants, so results may not apply to everyone. The main goal is measuring drug levels, not directly proving infection prevention.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, San Diego
RECRUITINGSan Diego, California, 92093, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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