Zapping resistant tumors may extend life of cancer drugs

NCT ID NCT06103669

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a precise local treatment—like focused radiation or ablation—can help people whose cancer has a few new or growing spots while on standard therapy. Participants continue their usual medication while the resistant tumors are treated directly. The goal is to see if this delays the need to switch or stop the current treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic ablative radiotherapy (SABR) or interventional radiology ablation therapy

What this could lead to

If successful, this approach could help people with certain cancers avoid switching systemic therapies for longer by treating resistant spots locally.

What could go wrong

This is a phase 2 study, so results are preliminary. Local therapy may cause side effects and not all patients may benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cancer female reproductive organ cancer head and neck cancer Head and Neck Neoplasms sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, Davis

    RECRUITING

    Sacramento, California, 95817, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact