Zapping resistant tumors may extend life of cancer drugs

NCT ID NCT06103669

Recruiting now Disease control Sponsor: University of California, Davis Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study tests whether adding a precise local treatment—like focused radiation or ablation—can help people whose cancer has a few new or growing spots while on standard therapy. Participants continue their usual medication while the resistant tumors are treated directly. The goal is to see if this delays the need to switch or stop the current treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stereotactic ablative radiotherapy (SABR) or interventional radiology ablation therapy
What this could lead to: If successful, this approach could help people with certain cancers avoid switching systemic therapies for longer by treating resistant spots locally.
What could go wrong: This is a phase 2 study, so results are preliminary. Local therapy may cause side effects and not all patients may benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cancer female reproductive organ cancer head and neck cancer Head and Neck Neoplasms sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER HEAD AND NECK CANCER OLIGOPROGRESSIVE OTHER CANCER SARCOMA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

University of California, Davis
RECRUITING

Sacramento, California, 95817, United States

Contact Email: •••••@•••••

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