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Kidney stone breakthrough? urine pH may predict shock wave success

NCT ID NCT07711028

Disease control Sponsor: Benha University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This study investigates whether the acidity of a person's urine influences how effectively shock wave lithotripsy (ESWL) can break up a single kidney stone smaller than 2 cm. Researchers will measure urine pH before treatment and track whether the stone is completely cleared. If a link is found, doctors might one day adjust urine pH beforehand to improve outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
shock wave lithotripsy (ESWL) using Siemens Lithoskop or piezoelectric lithotripter
What this could lead to
If urine pH proves to be a key factor, doctors could adjust it before treatment to boost the chance of breaking up kidney stones in one session.
What could go wrong
This is a single-center study with 146 participants, so results may not apply to everyone. The link between pH and stone clearance is still unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 146 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Single renal calculus. * Stones less than 2 cm in its maximum diameter. Exclusion Criteria: * Patients receiving any pH-altering medications. * Patients have multiple renal stones. * Patients have indwelling ureteral stents.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Shockwave therapy

Contacts and locations

Locations

  • Benha University Hospitals

    Banhā, Benha, 74111, Egypt

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