One lung or two? surgery trial aims to find the best approach for severe COPD

NCT ID NCT07731958

Recruiting now Disease control Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests whether operating on just one lung works as well as operating on both lungs for people with severe COPD and emphysema. The goal is to see if a less invasive approach can improve lung function with fewer risks. About 146 participants will be randomly assigned to one of the two procedures and followed for key outcomes like breathing capacity and survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lung volume reduction surgery (LVRS) performed on one or both lungs
What this could lead to: If one-lung surgery works as well as two-lung surgery, it could mean fewer complications and faster recovery for patients with severe COPD.
What could go wrong: This is a single-center trial with 146 participants, so results may not apply to all patients. Surgery carries risks like infection, air leaks, and serious complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease Dyspnea pulmonary emphysema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMPHYSEMA, PULMONARY

Contacts and locations

Locations

Rigshospitalet
RECRUITING

Copenhagen, 2300, Denmark

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