Gentle exercise with leg cuffs may offer a new path to rehab for COPD patients

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or Female * Aged 40 years or above * Diagnosed with COPD as per GOLD criteria (Forced expiratory volume(FEV1)/forced vital capacity(FVC) \<0.7) * FEV1 ≤ 80% predicted * Medical Research Council (MRC) dyspnoea scale ≥2 * BMI \<= 35 * Willing and able to give informed consent for participation in the study. * Stable dose of current regular medication for at least 4 weeks prior to study entry. * Clinically acceptable ECG at enrolment. * Able (in the investigators opinion) and willing to comply with all study requirements. * Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study. Exclusion Criteria: * Unable to communicate sufficiently in English * Unable to give informed consent or comply with testing and training protocol for any reason. * Acute exacerbation in the preceding 4 weeks (would become eligible 4 weeks following recovery). * Unable to undertake exercise due to physical or psychological barriers. * Contraindication to exercise training (American College of Sports Medicine guidelines) * Any major or uncontrolled comorbidity that would impair the participant's ability to exercise or would mean exercise was unsafe (e.g., uncontrolled diabetes, hypertension BP\>160/100, muscle or joint injuries which would limit ability to exercise). * Any other significant disease, disorder, or medical condition which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study including (but not limited to): Any clotting disorder Any bleeding disorder (e.g., haemophilia) Recent (\<3 months) venous thromboembolism, vascular (artery or vein) surgery to the legs, skin graft to the legs, and or arteriovenous fistula in the legs. Had one or both legs immobilisation in the last 4 weeks (e.g., prolonged bed rest, or recent orthopaedic intervention) Taking any anticoagulant medication Significant peripheral neuropathy * Current or within the last 3 months (or maximum relevant wash out period, whichever is longer), participation in an investigational medicinal product (IMP) or device trial at the time of screening. * Current or within the last 6 months (or maximum relevant wash out period, whichever is longer), participation in pulmonary rehabilitation or in another research study involving exercise training. * Scheduled elective surgery or other procedures requiring general anaesthesia during the study. * Female participants who are pregnant, lactating, or planning pregnancy during the course of the study.