The role of volumetric High-Resolution computed tomography (HRCT) of the chest in the assessment of patients with stable chronic obstructive pulmonary disease (COPD)

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:Patients with stable chronic obstructive pulmonary disease (COPD) Diagnosed according to GOLD criteria (post-bronchodilator FEV1/FVC \< 0.70) \- Exclusion Criteria: 1. Patient in exacerbation defined as change in the patient's baseline dyspnea, cough, and/or sputum beyond normal day-to-day variations within 14 days . (Ko, Fanny W., et al 2016) 2. Connective tissue disease . 3. Previously diagnosed Interstitial lung disease 4. Contraindication to PFT According to ATS (Stanojevic S., et al 2021) * Recent Myocardial Infarction Within 1 week * Blood Pressure Instability Severe hypertension or systemic hypotension * Arrhythmias Significant, uncontrolled atrial or ventricular arrhythmias * Decompensated heart failure * Pulmonary Circulation Issues: Uncontrolled pulmonary hypertension, acute cor pulmonale, or clinically unstable pulmonary embolism * History of Syncope Loss of consciousness related to coughing or forced expiration * Cerebral Aneurysm * Recent Brain Surgery: Within 4 weeks * Concussion: Recent concussion with prolonged symptoms * Eye Surgery: Recent eye surgery within 1 week * Pneumothorax: Active or untreated pneumothorax Recent Thoracic Surgery: Within 4 weeks Recent Abdominal Surgery: Within 4 weeks Late-Term Pregnancy 5. Contraindicatins of 6MWT according to ATS : Absolute contraindications * Unstable Angina Experienced during the previous 1 month. * Recent Myocardial Infarction : Within the previous 1 month. Relative contraindications * Resting Tachycardia: Resting heart rate \> 120{ bpm}. * Severe Uncontrolled Hypertension: * Systolic Blood Pressure \> 180{ mmHg} * Diastolic Blood Pressure \> 100{ mmHg} * Symptomatic/Severe Cardiac Conditions: High-degree atrioventricular (AV) block, hypertrophic cardiomyopathy, or symptomatic severe aortic stenosis.