Can we untangle the overlap of lung diseases? a new study aims to find out
NCT ID NCT06987266
First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time
Summary
This research project is looking at people with interstitial lung diseases (which affect the tissue around the air sacs) and airway diseases (like COPD). The goal is to better understand how these conditions often occur together and with other health problems. By studying a large group of patients, the researchers hope to create a clearer system for diagnosing and classifying these overlapping conditions. They will also track patients over time to see how the diseases progress and what factors affect prognosis, which could lead to better management strategies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better diagnostic criteria and classification systems for lung diseases, improving patient management and outcomes.
- What could go wrong
- This is an observational study, so it won't test a new treatment. The findings may not change clinical practice immediately, and the complexity of these diseases could limit the generalizability of the results.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 900 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Among the inpatient or outpatient patients in 9 Grade A hospitals, at least 900 patients with COPD combined with/uncombined interstitial lung abnormalities, idiopathic pulmonary fibrosis combined with/uncombined airway disease, nonspecific interstitial pneumonia combined with/uncombined airway disease, pulmonary fibrosis combined with emphysema syndrome.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. age between 40-80 years old; 2. inpatients with an admission diagnosis of COPD, Idiopathic pulmonary fibrosis, nonspecific interstitial pneumonia, patients with the following diagnoses were screened by chest CT (slice thickness ≤1.5 mm) during hospitalization and by in-hospital or prior pulmonary function; 3. Inpatients who meet the criteria can complete pulmonary function tests and chest HRCT examinations within one month before expected discharge (excluding hospitalized patients with stable interstitial lung disease or airway disorders); 4. among outpatients, patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, nonspecific interstitial pneumonia, COPD with pulmonary interstitial abnormalities, idiopathic pulmonary fibrosis with airway lesions, nonspecific interstitial pneumonia with airway lesions, pulmonary fibrosis with emphysema syndrome were diagnosed through chest CT (layer thickness ≤1.5mm) and lung function; 5. provide informed consent. Exclusion Criteria: 1. expected survival less than 12 months; 2. planned lung transplantation or pneumonectomy within 12 months; 3. pregnant or lactating women; 4. Has previously undergone lobectomy or received thoracic radiotherapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Xiangya Hospital
RECRUITINGChangsha, Hunan, 410008, China
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